PSA Test Options for Prostate Cancer Screening

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Match the PSA measurement to your reason for testing

Each of these answers a different PSA question — a screening value, added detail, or ongoing follow-up.

Want a straightforward PSA screening value? one result: your total PSA, with nothing else measured View Total PSA Test $115 $92
Comparing free PSA against the total? adds free PSA and percent free PSA, which expresses that relationship View Free and Total PSA $93 $74
Following your PSA after prostate surgery? an ultrasensitive method, for watching your own value over time View Ultrasensitive PSA Test $113 $90
Prefer a structure-based PSA test? View IsoPSA Test $3,906 $3125

Featured tests

HSA/FSA accepted

Prostate Health Check (PSA)

Pinpoint prostate health issues early
Reveal potential cancer risks effortlessly
Confirm peace of mind about your health

• All lab fees included

-20% $92 about $13 per marker

List price ~~$115~~

HSA/FSA accepted

Prostate-Specific Antigen (PSA), Free and Total (MALES ONLY)

Detect prostate issues early for peace of mind
Unveil hidden health risks effortlessly
Confirm your prostate health with certainty

• All lab fees included

-20% $74 about $3 per marker

List price ~~$93~~

HSA/FSA accepted

Prostate-Specific Antigen (PSA), Ultrasensitive, Post Prostatectomy (MALES ONLY)

Pinpoint any remaining prostate cancer cells
Verify your recovery progress post-surgery
Highlight areas needing further treatment

• All lab fees included

-20% $90 about $6 per marker

List price ~~$113~~

HSA/FSA accepted

IsoPSA®

Assess your prostate cancer risk
Clarify unclear PSA test results
Screen for aggressive prostate conditions

-20% $3125

List price ~~$3,906~~

HSA/FSA accepted

PSA, Total (2.5 ng/mL cutoff)

Screen for prostate cancer risk
Check urinary symptom causes
Monitor prostate health yearly

HSA/FSA accepted

-20% $39

List price ~~$49~~

PSA tests measure prostate-specific antigen (PSA) in blood. Options range from total PSA alone to free PSA and percent free PSA, while an ultrasensitive assay is intended for post-prostatectomy monitoring. People compare them when deciding whether they need a straightforward screening measurement, added information for interpreting a total PSA result, or follow-up after prostate surgery. A PSA test supports screening or monitoring; it does not diagnose prostate cancer by itself. Start with the clinical question: total PSA screening, free and total PSA comparison, or ultrasensitive PSA after prostatectomy. Discuss concerning results or symptoms with a qualified healthcare professional.

What PSA measurements tell you

Prostate-specific antigen, or PSA, is measured in blood and is used to support prostate cancer screening discussions and to monitor PSA over time. The Prostate-Specific Antigen (PSA) (MALES ONLY) test measures PSA, Total. The Prostate-Specific Antigen (PSA), Free and Total (MALES ONLY) test measures PSA, Total, PSA, Free, and PSA, % Free. Free PSA is the portion measured separately from total PSA, and percent free PSA expresses that relationship. These results add detail to a total PSA result, but no PSA measurement confirms or rules out cancer on its own. A clinician considers the result, prior values, symptoms, examination findings, and other relevant factors.

Screening, repeat testing, and post-prostatectomy follow-up

The purpose of testing shapes the most useful measurement. Total PSA is a direct choice when the question is a current PSA value for screening discussion or comparison with a prior total PSA result. Free and total PSA adds PSA, Free and PSA, % Free when more than a total value is requested. After prostatectomy, the Prostate-Specific Antigen (PSA), Ultrasensitive, Post Prostatectomy (MALES ONLY) test measures PSA by an ultrasensitive method for follow-up. Comparing results over time is most meaningful when a healthcare professional reviews the testing history and the reason for monitoring. New urinary symptoms, pelvic pain, or other concerning symptoms deserve prompt medical evaluation rather than relying on PSA alone.

Prostate Cancer Screening & PSA Tests FAQ

A PSA test measures prostate-specific antigen in blood. PSA, Total reports the overall measured amount, while PSA, Free reports the separately measured free portion and PSA, % Free reports its relationship to total PSA. These measurements support screening discussions or follow-up, but they do not diagnose prostate cancer by themselves.

The total PSA test reports PSA, Total only. The free and total PSA test reports PSA, Total, PSA, Free, and PSA, % Free, providing additional values for interpreting a total PSA result. The added measurements do not independently establish a diagnosis; a qualified professional should interpret them with your history and prior PSA results.

An ultrasensitive PSA test is designed for post-prostatectomy PSA monitoring. The Prostate-Specific Antigen (PSA), Ultrasensitive, Post Prostatectomy (MALES ONLY) test measures PSA by an ultrasensitive method, making it distinct from the standard total PSA option. It is best selected when the clinical question specifically concerns follow-up after prostatectomy.

No, a PSA test does not diagnose prostate cancer by itself. PSA results are used to support screening or monitoring and need interpretation alongside factors such as prior PSA values, symptoms, examination findings, and other clinical information. A result outside an expected range has several possible explanations and warrants professional review.

A sequence of PSA results helps a clinician evaluate change rather than relying on one measurement alone. A single PSA value can be influenced by factors unrelated to cancer, so the timing and pattern of results matter. Use the same named measurement when comparison with a prior result is the goal, and seek professional guidance for interpretation.

PSA, % Free expresses the measured free PSA portion in relation to PSA, Total. It is available with the Prostate-Specific Antigen (PSA), Free and Total (MALES ONLY) test, along with the separate PSA, Free value. It gives a clinician more information to consider than total PSA alone, without serving as a diagnosis.

PSA, Total (2.5 ng/mL cutoff) is a named total PSA testing option with a 2.5 ng/mL cutoff in its title. It is different from the free and total PSA test because it does not report PSA, Free or PSA, % Free. A cutoff does not replace individualized interpretation of a PSA result.

A standard total PSA test measures the concentration of prostate-specific antigen in blood. IsoPSA evaluates structural forms of PSA and is designed to help distinguish a higher likelihood of high-grade prostate cancer from lower-grade cancer or benign conditions. It is a specialized risk-assessment test, not a diagnosis, so the result should be interpreted by a qualified healthcare professional with other clinical findings.

Ordering & Results FAQ

You'll receive it via email within 60 seconds of your order unless it requires additional processing (only very complex orders do).

Many general wellness test results are typically available online within 2-3 business days. However, some tests will require additional processing time. You will immediately receive an email & SMS notification when your results are available.

We do not share your results with your physician, insurance company, or any other third party.