A Lyme disease test evaluates laboratory evidence related to Borrelia exposure or infection, depending on the method selected. Options here include a Lyme Ab Screen with reflex testing, IgG and IgM immunoblot band results, an antibody immunoassay pathway, Borrelia species DNA testing in blood, and a tick-borne disease antibody panel with reflexes. People often compare these choices after a tick exposure, persistent symptoms, prior antibody findings, or a request for a more specific laboratory method. Start by deciding whether the question concerns antibodies, individual immunoblot bands, or Borrelia DNA in blood.
Antibody screening and immunoblot results
The Lyme Disease Antibody with Reflex to Antibodies IGG & IGM Blot measures a Lyme Ab Screen and uses reflex testing to IgG and IgM blot methods. The Lyme Disease Antibodies (IgG, IgM), Immunoblot reports separate antibody-band findings: IgM 23, 39, and 41 Kd bands, along with IgG 18, 23, 28, 30, 39, 41, 45, 58, 66, and 93 Kd bands. Those individual findings provide a more detailed antibody pattern than a single screen result. Antibody results need to be considered with timing of exposure, symptoms, and clinical history; they do not establish a diagnosis on their own.
When DNA testing answers a different question
Borrelia Species DNA, Real-Time PCR, with Reflexes, Blood looks for Borrelia species DNA in a blood specimen. That is a different measurement from antibodies, which reflect an immune response. A DNA result and an antibody result therefore should not be treated as interchangeable findings. The product name specifies real-time PCR with reflexes, while the antibody tests specify a Lyme Ab Screen, immunoassay, or immunoblot antibody testing. For symptoms or results that require medical decisions, professional review helps relate the laboratory method and result to the full clinical picture.
Other tick-related testing choices
The Tick-Borne Disease Antibodies Panel with Reflexes is an antibody panel with reflexes for a tick-borne disease testing question that extends beyond a Lyme-only antibody screen. The Lyme Disease Antibody with Reflex to Immunoassay (IgG, IgM) (MTTT) instead follows an antibody pathway explicitly named for IgG and IgM immunoassay testing. These distinctions matter because one option is labeled as a tick-borne disease antibody panel, while the other is labeled for Lyme disease antibodies and an IgG/IgM immunoassay reflex. Neither type of laboratory result alone diagnoses the cause of symptoms.