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Lyme disease DNA testing for families experiencing unexplained symptoms like fatigue and joint pain

Lyme Disease DNA Test for Tick Bites and Unexplained Symptoms

Borrelia Species DNA, Qualitative Real-Time PCR, Miscellaneous

Google
3,138 reviews
  • Detects Lyme disease DNA in blood
  • Checks for Lyme-causing bacteria DNA
  • Identifies Borrelia bacteria presence quickly
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained symptoms after a tick bite or outdoor exposure, such as persistent fatigue, joint pain, muscle aches, fever, or a bullseye rash. It detects the DNA of Borrelia bacteria, which causes Lyme disease, helping confirm or rule out an active infection. Many people use this test when they suspect Lyme disease but want concrete answers, especially if standard antibody tests haven't provided clear results.

How should I prepare for this test?

No special preparation is typically required for this DNA test. You don't need to fast or avoid medications unless specifically instructed by your healthcare provider. If you're currently taking antibiotics for suspected Lyme disease, consult with your doctor about timing, as treatment may affect test results.

What's included in this test?

This PCR test uses advanced molecular technology to detect the genetic material (DNA) of Borrelia bacteria directly in your blood sample. Unlike antibody tests that look for your immune response, this test identifies the actual presence of the bacteria, making it particularly useful for early or active infections. It provides a qualitative result, meaning it tells you whether Borrelia DNA was detected or not detected.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining whether Borrelia DNA was detected and what that means for your health. These notes include personalized recommendations like whether you need antibiotic treatment, follow-up testing, or additional evaluation by an infectious disease specialist. You'll also get the standard lab report and can track your testing history over time using our trends feature, which is especially helpful if you're monitoring treatment progress or need repeated testing.
Who should consider getting this test?
This test is ideal for people who've had recent tick exposure or live in areas where Lyme disease is common, especially if experiencing symptoms like persistent fatigue, joint swelling, neurological issues, or a spreading rash. It's also valuable for those whose antibody tests came back negative but symptoms persist, since PCR can detect active infection earlier than antibody tests. Anyone with chronic unexplained symptoms after outdoor activities in wooded or grassy areas should consider this testing.
What symptoms indicate I may need this test?
Common symptoms that warrant testing include a bullseye rash (erythema migrans), unexplained fever, severe headaches, extreme fatigue, muscle and joint aches, or swollen lymph nodes after potential tick exposure. Later-stage symptoms can include facial paralysis, heart palpitations, nerve pain, memory problems, or persistent arthritis. If you have flu-like symptoms that don't improve or neurological changes after spending time outdoors, this test can help identify if Lyme disease is the cause.
What is Lyme disease and why does early detection matter?
Lyme disease is an infection caused by Borrelia bacteria transmitted through tick bites, most commonly from deer ticks. Early detection and treatment with antibiotics can prevent the infection from spreading to your joints, heart, and nervous system. If left untreated, Lyme disease can cause chronic problems including severe arthritis, cognitive difficulties, and long-term fatigue, which is why identifying it quickly is crucial for successful treatment.
What does a positive result mean?
A positive result means Borrelia DNA was detected in your blood, indicating an active Lyme disease infection. This requires prompt medical attention and typically antibiotic treatment prescribed by your healthcare provider. Your doctor will determine the appropriate antibiotic regimen based on your symptoms and how long you've likely been infected, with early-stage infections usually responding very well to treatment.
What does a negative result mean?
A negative result means no Borrelia DNA was detected in your blood sample at the time of testing. However, if symptoms persist and Lyme disease is still suspected, your doctor may recommend retesting or additional antibody tests, as the bacteria may be present in tissues rather than circulating blood. PCR tests are most accurate when performed during active infection, particularly in early-stage disease.
How can I reduce my risk of Lyme disease?
Prevent tick bites by wearing long sleeves and pants when in wooded or grassy areas, using EPA-approved insect repellent, and staying on cleared trails. Check yourself, children, and pets thoroughly for ticks after outdoor activities, and remove any attached ticks promptly with fine-tipped tweezers. Showering within two hours of coming indoors and putting outdoor clothes in a hot dryer can also help kill undetected ticks before they attach.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Borrelia Species DNA Not Detected
Demo results
Not Detected Detected
Not Detected

What this means

Your test came back negative, meaning no Borrelia bacteria DNA was detected in your blood. This is the expected and healthy result, suggesting you do not have an active Lyme disease infection at this time.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Lyme Disease DNA Test for Tick Bites and Unexplained Symptoms

Google
3,138 reviews
  • Detects Lyme disease DNA in blood
  • Checks for Lyme-causing bacteria DNA
  • Identifies Borrelia bacteria presence quickly

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.