Get $200 with your 1st order. Same day blood tests, next day results. Google reviews

Private MD News

Home | News | Cancer Detection and Tumor Markers

Drug testing study shows reduced occurrence of brain tumors

Category: Cancer Detection and Tumor Markers

Lab testing of the drug vorinostat demonstrated that the medication is able to cross the blood-brain barrier and reduce the occurrence of metastatic tumors in mice.

The new study, which appears in the September 29 online issue of Clinical Cancer Research, demonstrated that vorinostat reduced the development of large metastatic tumors in mice by 62 percent compared a group of mice that did not receive the drug.

For humans, vorinostat has been FDA approved for the treatment of cutaneous T-cell lymphoma, but has only been used experimentally as treatment of other cancers. The researchers, from the National Cancer Institute, say that this study may provide insight regarding the prevention of breast cancer's spread to the brain in diseased patients. Brain metastases of breast cancer have been untreatable because of the blood-brain barrier.

"Drugs that can cross the blood-brain barrier and reduce the size and incidence of metastatic tumors are urgently needed," said Dr Patricia S. Steeg, the study's author. Researchers believe the drug works by breaking strands of DNA and lowering the function of a repair gene, preventing cancer cells from restoring and metastasizing.

The National Institutes of Health determined that about 20 percent of breast cancer patients diagnosed with brain metastases survive past one year.


Related Articles from Private MD:

News Categories:

Advanced Lipid Treatment I   Allergy Testing   Anemia and RBC disorders   Autoimmune Diseases   Bariatric Lab Testing   Blood and Blood Diseases   Breast   Cancer Detection and Tumor Markers   Celiac Disease Testing   Chlamydia   Coagulation and blood clotting disorders   Colon   DNA, Paternity and Genetic testing   Diabetes   Drug Screening   Environmental Toxin Testing   Female Specific Tests   Gastrointestinal Diseases   General Health   General Wellness   HIV   HIV monitoring/Treatment/Testing/Post Diagnos   Heart Health and Cholesterol   Herpes   Hormones and Metabolism   Infectious Diseases   Infertility Testing-Male   Infertitlity Hormone Testing   Kidney Diseases   Leukemia and WBC disorders   Liver   Liver Diseases   Lyme Disease   Male Specific Tests   Menopause/Peri-Menopausal Diagnosis   Musculoskeletal Diseases   Nicotine Screening   Organ Specific Testing   Ovarian   Prostate   Prostate   Sexually Transmitted Diseases   Thyroid Diseases   Transgender Hormone Testing-Male to Female   Transgender Hormone Testing-female to male   Vitamin D Deficiency-Diagnosis and Treatment   

Visit the Health News Archive: Click Here

Questions about online blood testing or how to order a lab test?

Speak with our Wellness Team: (877) 283-7882
Back to top