Call us: 1.877.283.7882 | Monday–Friday: 8:00 AM–4:30 PM ET

Private MD News

Home | News | General Health

Gene therapy roots out emphysema in clinical tests

Category: General Health

Genetic testing for mutations which are responsible for causing emphysema may lead to a single-treatment therapy which provides lifetime protection against the progression of the lung disease, according to recent research.

In the background information to a study published in the December 21 online issue of the Journal of Clinical Investigation, scientists from the Boston University School of Medicine identified a mutation in the alpha-1 anti-trypsin gene as the most common cause of emphysema in young adults, HealthDay News reports.

During their study, the team of researchers was able to develop a system that selectively delivered therapeutic genes to as many as 70 percent of the lung's alveolar macrophages, the white blood cells which play a role in emphysema development.

"The lung macrophages carrying the therapeutic gene survived in the lungs' air sacs for the two-year lifetime of the treated mice following a single injection of the [system] we had engineered," said the study's senior author Dr Darrell Kotton, co-director of the Center for Regenerative Medicine at Boston University.

According to Dr Andrew Wilson, the study clarifies that lung macrophages may be targeted for further studies on gene therapy.
The Centers for Disease Control and Prevention reports that emphysema kills more than 12,000 Americans each year.
ADNFCR-2248-ID-19527036-ADNFCR

Related Articles from Private MD:

Share on Facebook

Subscribe to Private MD Health News RSS Feed: Subscribe

News Categories:

Advanced Lipid Treatment I   Allergy Testing   Anemia and RBC disorders   Autoimmune Diseases   Bariatric Lab Testing   Blood and Blood Diseases   Breast   Cancer Detection and Tumor Markers   Celiac Disease Testing   Chlamydia   Coagulation and blood clotting disorders   Colon   Diabetes   DNA, Paternity and Genetic testing   Drug Screening   Environmental Toxin Testing   Female Specific Tests   Gastrointestinal Diseases   General Health   General Wellness   Heart Health and Cholesterol   Herpes   HIV   HIV monitoring/Treatment/Testing/Post Diagnos   Hormones and Metabolism   Infectious Diseases   Infertility Testing-Male   Infertitlity Hormone Testing   Kidney Diseases   Leukemia and WBC disorders   Liver   Liver Diseases   Lyme Disease   Male Specific Tests   Menopause/Peri-Menopausal Diagnosis   Musculoskeletal Diseases   Organ Specific Testing   Ovarian   Prostate   Sexually Transmitted Diseases   Thyroid Diseases   Transgender Hormone Testing-female to male   Transgender Hormone Testing-Male to Female   Vitamin D Deficiency-Diagnosis and Treatment   

Visit the Health News Archive: Click Here

Questions about online blood testing or how to order a lab test? Click here to get started or call us toll-free at 1.877.283.7882. Our professionals are ready to assist you.

Back to top