Call us: 1.877.283.7882 | Monday–Friday: 8:00 AM–4:30 PM ET

Private MD News

Home | News | Breast

Researchers may have found a way to treat tamoxifen-resistant breast cancer

Category: Breast

Diagnosis of breast cancer through a lab test is one of the first steps patients can take toward treating their disease. Some patients may benefit from drugs such as tamoxifen, but over time, the disease may become resistant to this therapy.

Recently, researchers from Ohio State University discovered an alternative approach to treating breast cancer that no longer responds to tamoxifen.

More than two-thirds of breast cancer cases are estrogen-receptor positive, meaning they grow in response to the hormone estrogen. Tamoxifen usually blocks this process, but up to 40 percent of patients become resistant after five years. This may be because alternative pathways in the cancer cells allow the disease to thrive.

However, new experiments demonstrated that shutting down two other cellular pathways, known as hedgehog and PI3K/AKT, can help eliminate the tamoxifen-resistant cancer.

Vismodegib, a drug currently in clinical trials, may be able to achieve this effect.

Until researchers learn more about this agent, patients who think they have or are at risk for breast cancer should consider undergoing a lab test. If they are positive, a healthcare provider can help them go over their treatment options.

Related Articles from Private MD:

Share on Facebook

Subscribe to Private MD Health News RSS Feed: Subscribe

News Categories:

Advanced Lipid Treatment I   Allergy Testing   Anemia and RBC disorders   Autoimmune Diseases   Bariatric Lab Testing   Blood and Blood Diseases   Breast   Cancer Detection and Tumor Markers   Celiac Disease Testing   Chlamydia   Coagulation and blood clotting disorders   Colon   Diabetes   DNA, Paternity and Genetic testing   Drug Screening   Environmental Toxin Testing   Female Specific Tests   Gastrointestinal Diseases   General Health   General Wellness   Heart Health and Cholesterol   Herpes   HIV   HIV monitoring/Treatment/Testing/Post Diagnos   Hormones and Metabolism   Infectious Diseases   Infertility Testing-Male   Infertitlity Hormone Testing   Kidney Diseases   Leukemia and WBC disorders   Liver   Liver Diseases   Lyme Disease   Male Specific Tests   Menopause/Peri-Menopausal Diagnosis   Musculoskeletal Diseases   Organ Specific Testing   Ovarian   Prostate   Sexually Transmitted Diseases   Thyroid Diseases   Transgender Hormone Testing-female to male   Transgender Hormone Testing-Male to Female   Vitamin D Deficiency-Diagnosis and Treatment   

Visit the Health News Archive: Click Here

Questions about online blood testing or how to order a lab test? Click here to get started or call us toll-free at 1.877.283.7882. Our professionals are ready to assist you.

Back to top