What's this test for?

This test is ideal if you're experiencing unexplained balance problems, dizziness, clumsiness, or difficulty coordinating movements that came on relatively quickly. It looks for Yo antibodies, which are linked to a rare condition called paraneoplastic cerebellar degeneration, a nervous system disorder that can occur alongside certain cancers. Your results, combined with your symptom history, help figure out if this uncommon cause needs further attention.

What happens after I get my results?

Your results will appear in your online account, with each value explained alongside its normal range so you understand what a positive or negative result means. If Yo antibodies are detected, this is a signal to seek further medical care right away since it can be associated with underlying conditions that need prompt attention. You can download a standard lab report from your account at any time, and if retesting is ever needed, you can track results over time using the trends feature.

Who should consider this test?

This test is a good option for people who have sudden, unexplained problems with balance, coordination, or eye movement that doctors haven't been able to explain with more common causes. It's also useful for people with a personal history of ovarian, uterine, small cell lung cancer, or Hodgkin's lymphoma who develop new neurological symptoms. If a specialist has raised concerns about a paraneoplastic syndrome, this test can provide helpful information.

What symptoms indicate I may need this test?

Common symptoms linked to this condition include sudden clumsiness, unsteady walking, slurred speech, double vision, and difficulty with fine motor tasks like writing or buttoning a shirt. Some people also notice dizziness or a spinning sensation that doesn't go away. If these symptoms appeared quickly and don't have an obvious cause, this test can help identify whether Yo antibodies are playing a role.

When will I get my results?

Results for this test are typically ready within about 7 days of your sample being processed at the lab. Because this test may include a reflex to titer and Western Blot confirmation if the initial screen is positive, turnaround can occasionally take a bit longer. You'll get a notification as soon as your results are available in your secure online account.

What is paraneoplastic cerebellar degeneration and why does it matter?

Paraneoplastic cerebellar degeneration is a rare condition where the immune system, while fighting a tumor, mistakenly attacks healthy cells in the cerebellum, the part of the brain that controls balance and coordination. This can cause serious movement and speech problems that sometimes appear before a cancer is even diagnosed. Catching it early matters because identifying the antibody can point to an underlying cancer that needs prompt treatment.

What does a positive Yo antibody result mean?

A positive result means Yo antibodies were found in your blood, which is strongly associated with paraneoplastic cerebellar degeneration and certain cancers like ovarian, uterine, small cell lung cancer, or Hodgkin's lymphoma. This doesn't confirm cancer on its own, but it's an important finding that calls for prompt follow-up imaging and further testing. Because of the seriousness of this result, you should seek medical care as soon as possible.

What causes a positive Yo antibody result?

A positive result happens when your immune system produces antibodies that target Purkinje cells in the cerebellum, usually triggered by the body's immune response to a tumor elsewhere. This is called a paraneoplastic reaction because the antibodies form as a side effect of the body fighting the cancer, not from the cancer directly invading the brain. Finding these antibodies often prompts a search for an underlying, sometimes undiagnosed, tumor.

How often should I retest?

This isn't a routine test that needs regular repeating for most people since it's used to investigate specific, unusual neurological symptoms. If your first result is negative but symptoms persist or worsen, retesting or additional evaluation may be worthwhile. If you've already tested positive and are undergoing treatment, retesting may be used later to help track how you're responding, based on guidance from your treatment plan.

What should I do if my results are abnormal?

If your Yo antibody screen comes back positive, treat it as urgent and seek medical care promptly, since this result is linked to serious underlying conditions. Bring your lab report with you, as it clearly outlines your value and what it means. In the meantime, keep track of any new or worsening symptoms like balance changes or vision problems so you can describe them accurately during follow-up care.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Yo Antibody Test - Cerebellar & Cancer-Linked Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Yo Antibody Test for Paraneoplastic Neurological Symptoms

Yo Antibody Screen with Reflex to Titer and Western Blot

Prescription & fees included

Easy to understand results

Fast & convenient

Prescription & fees included

Easy to understand results

Fast & convenient

What's this test for?

What happens after I get my results?

Who should consider this test?

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

Find a lab near you

Yo Antibody Test for Paraneoplastic Neurological Symptoms

Prescription & fees included

Easy to understand results

Fast & convenient

1,000,000+ blood tests later, here's what our customers say