What's this test for?

This test is ideal if you or someone you know has been diagnosed with a tumor and the origin of the cancer isn't clear from other testing. Villin IHC is a specialized tissue stain used by pathologists to help figure out whether a cancer started in the intestines or kidneys versus other organs like the lungs, breast, or ovaries. This is typically ordered as a follow-up to a biopsy when more clarity is needed about where a cancer originated.

What's included in this test?

This test involves a single specialized stain that highlights villin, a structural protein found in the lining of the intestines and kidneys. Pathologists use this stain because certain cancers keep the biological fingerprints of the tissue they originated from, so seeing villin can help narrow down where a tumor started. This is especially useful when a cancer has spread and the original site isn't obvious from imaging alone.

What happens after I get my results?

Your results will be available in your account, and the report explains what the staining pattern means in plain terms. Because this is a specialized tissue marker rather than a simple high/low blood value, the report focuses on whether the tissue sample showed positive or negative staining and what that suggests about the tissue's origin. You can download the standard lab report directly from your account at any time, and if additional related testing is done later, you can track those results together over time using the trends feature.

How can I naturally support digestive and intestinal health?

While this test itself doesn't measure lifestyle-related markers, keeping your intestinal lining healthy in general can support overall wellness. Eating plenty of fiber, staying hydrated, and limiting ultra-processed foods can help maintain a healthy gut lining. Regular movement and reducing alcohol intake also support digestive tissue health over time.

When will I get my results?

Results for this specialized tissue stain are typically ready within about 7 days after your sample is processed at the lab. Because this involves detailed microscopic examination rather than a quick blood measurement, it takes a bit longer than routine panels. You'll be notified as soon as your report is available in your account.

Who should consider this test?

This test is generally considered when a tumor has already been found and there's a need to pinpoint whether it originated from the intestines, kidneys, bladder, or ovaries versus the lungs or breast. It's most relevant for people who have had a biopsy showing cancer cells but whose origin site is uncertain. This is a specialized diagnostic step rather than a routine screening test.

What symptoms might lead someone to need this type of testing?

People typically pursue this kind of specialized tissue testing after imaging or a biopsy has already revealed a mass or unusual growth, not because of specific everyday symptoms. Symptoms that might have led to the original workup include unexplained weight loss, digestive changes, blood in stool or urine, or persistent abdominal discomfort. This villin stain is a follow-up step to help characterize a tumor that's already been identified.

What does a positive villin result mean?

A positive villin stain suggests that the tumor cells share characteristics with tissue from the intestines or kidneys, which can help confirm where a cancer originated. This is helpful information because treatment approaches often depend on identifying the original cancer type. It's one piece of a larger diagnostic puzzle rather than a stand-alone diagnosis.

What does a negative villin result mean?

A negative result means the tumor cells didn't show the villin marker, which can help rule out an intestinal or kidney origin for the cancer. This narrows down the possibilities and helps guide what other tests might be considered next. Negative results are still valuable because they help exclude certain possibilities.

What should I do if my results raise concerns?

If your report shows findings you don't fully understand or that raise questions about next steps, it's a good idea to seek medical care promptly so the full clinical picture can be considered together with your other test results. Keep a copy of your downloadable report handy since it may be useful for coordinating any follow-up testing. Tracking all related results together over time can help make sense of the full picture.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Villin IHC Test - Identify Cancer Tissue Origin

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Villin IHC Tissue Stain Test for Cancer Origin

Villin, IHC without Interpretation

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

What's this test for?

What's included in this test?

What happens after I get my results?

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Villin IHC Tissue Stain Test for Cancer Origin

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

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