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Lab test for patients on ustekinumab monitoring drug levels and antibodies

Ustekinumab Drug Level & Antibody Blood Test

Ustekinumab Level and Anti-drug Antibody

  • Check ustekinumab drug levels accurately
  • Screen for treatment antibody problems
  • Monitor psoriasis and Crohn's response
$2266
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're currently being treated with ustekinumab (Stelara or an approved biosimilar) for psoriasis, ulcerative colitis, or Crohn's disease and your symptoms are not fully under control. It helps check whether your body has enough of the drug in your system and whether you've developed antibodies that could be blocking the medication from working. This is especially useful if your condition seems to be flaring up despite staying on treatment.

What happens after I get my results?

Your results will appear in your account with both the ustekinumab level and the anti-drug antibody result, along with the ranges that are considered optimal for your type of condition. If your drug level is low or antibodies are detected, simple next steps include reviewing your dosing schedule and timing of your last dose, since these directly affect trough levels. You can download a standard lab report from your account at any time, and if you retest in the future you'll be able to track your levels over time using the trends feature to see how changes in treatment affect your results.

Who should consider this test?

Anyone on ustekinumab therapy whose symptoms have returned or never fully improved is a good candidate for this test. It's also useful for people who want to confirm their drug levels are in a helpful range before considering a dose change. People switching between brand-name ustekinumab and a biosimilar may also want to check that their levels remain consistent.

What symptoms indicate I may need this test?
If your psoriasis plaques are returning, or if you're having more digestive flare-ups like abdominal pain, diarrhea, or blood in your stool while on ustekinumab, this test can help explain why. Fatigue, joint pain, or a general sense that your treatment isn't working as well as it used to are also reasons to check your levels. These symptoms can sometimes mean your body isn't holding onto enough of the drug or has built antibodies against it.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification once your report is available in your account. Because this is a specialized test, it can take a little longer than routine bloodwork, so plan any treatment decisions around this timeline.
What is ustekinumab drug monitoring and why does it matter?
Ustekinumab drug monitoring measures how much active medication is circulating in your blood right before your next dose, called the trough level. This matters because having too little drug in your system is one of the most common reasons treatment stops working well, even if you're taking it exactly as prescribed. Knowing your level can help explain unexpected flare-ups and guide conversations about adjusting your treatment plan.
What does a low ustekinumab level mean?
A low trough level means there isn't much active drug left in your body by the time your next dose is due, which can make it harder to keep your condition under control. For psoriasis, levels below roughly 0.6 mcg/mL are linked to a weaker response, while for inflammatory bowel disease the helpful range is generally higher, around 1.0 to 4.5 mcg/mL. If your level comes back low, it may be worth discussing whether your dosing frequency or amount needs adjusting.
What causes low ustekinumab levels or high anti-drug antibodies?
Low levels can happen simply because the drug clears out of your system faster than expected, or because your dose and timing don't quite match your body's needs. Anti-drug antibodies are the immune system's response to treating the medication as a foreign substance, and when these antibodies are present they can speed up how quickly the drug is cleared. Missing doses or long gaps between treatments can also contribute to lower levels over time.
How often should I retest my ustekinumab levels?
There's no universal schedule, but many people retest when symptoms change or before making a decision to adjust dosing. If your levels and antibody status are stable and your symptoms are well controlled, less frequent testing is generally reasonable. Using the trends feature in your account can help you and your care team see patterns over multiple tests.
What should I do if my results are abnormal?
If your trough level is lower than the optimal range or antibodies are detected, note the timing of your last dose and any recent symptom changes, since this context is helpful for future testing. Keeping a consistent dosing schedule and avoiding missed doses can help maintain steadier drug levels. If you're having severe symptoms like significant abdominal pain, heavy bleeding, or a widespread psoriasis flare, seek medical care promptly rather than waiting for a routine follow-up.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Ustekinumab Trough Level 0.4 mcg/mL
Demo results
Low (<0.6 mcg/mL) Optimal (0.6-4.5 mcg/mL) High (>4.5 mcg/mL)
0.4 mcg/mL

What this means

This result shows a lower-than-optimal amount of ustekinumab in the blood at trough, which is linked to a weaker treatment response. Levels like this are more common when doses are missed, spaced too far apart, or when the drug is clearing faster than expected. Anti-drug antibodies can also contribute to lower levels and are worth checking alongside this result.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
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Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Ustekinumab Drug Level & Antibody Blood Test

  • Check ustekinumab drug levels accurately
  • Screen for treatment antibody problems
  • Monitor psoriasis and Crohn's response
$2266
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.