What's this test for?

This test is ideal if you're experiencing unexplained episodes of mild jaundice, yellowing of the eyes or skin, or if you've been told your bilirubin levels run high without a clear cause. It's also helpful if you or someone in your family is about to start chemotherapy with a drug called Irinotecan, since certain genetic patterns can make side effects from this medication much more severe. This test looks at your genes to explain why your body processes bilirubin the way it does.

What's included in this test?

This test analyzes a specific gene involved in how your liver breaks down bilirubin, a natural waste product from red blood cells. Understanding your genetic pattern here matters because it explains both harmless conditions like Gilbert syndrome and more serious concerns like how your body might react to certain chemotherapy drugs.

What happens after I get my results?

Your results will show up in your account along with a plain-language explanation of what your specific genetic pattern means. If your results point to Gilbert syndrome, the report will explain that this is generally a harmless condition and outline simple lifestyle habits that help keep bilirubin levels steady, such as staying hydrated and avoiding long fasting periods. If your results show an increased sensitivity to Irinotecan, that information can guide dosing conversations before treatment starts. You can download a standard lab report anytime and use the trends feature if you ever retest in the future.

How can I naturally support healthy bilirubin processing?

Staying well hydrated and eating regular meals can help prevent the mild bilirubin spikes some people notice with Gilbert syndrome, since fasting and dehydration are common triggers. Getting consistent sleep and managing stress also seem to help, as exhaustion and illness can temporarily raise bilirubin in sensitive individuals. Limiting alcohol gives your liver less extra work to do. None of these steps are required, but many people find them useful for feeling their best.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed at the lab. Genetic tests like this one take a bit longer than standard blood work because of the detailed analysis involved. You'll get a notification as soon as your results are posted to your account.

Who should consider this test?

This test is worth considering if you have recurring mild jaundice or elevated bilirubin on previous lab work with no obvious explanation. It's also valuable for anyone scheduled to receive Irinotecan chemotherapy, since knowing your genetic pattern beforehand can help avoid severe side effects. Family members of someone diagnosed with Gilbert syndrome may also want to check their own genetic status.

What symptoms indicate I may need this test?

Watch for intermittent yellowing of the skin or eyes, especially during times of stress, illness, fasting, or dehydration, which are classic signs of Gilbert syndrome. Some people also notice mild fatigue or stomach discomfort during these episodes, though many people have no symptoms at all and only find out through routine lab work. If you're facing chemotherapy and want to understand your risk of stronger side effects ahead of time, that's also a good reason to test.

What is Gilbert syndrome and why does it matter?

Gilbert syndrome is a common, usually harmless genetic trait where your liver processes bilirubin a bit more slowly than average, leading to occasional mild jaundice. It matters because it's often mistaken for liver disease, causing unnecessary worry or additional testing. Knowing you have this genetic pattern can save you from confusion the next time a routine blood test shows slightly high bilirubin.

What does an abnormal UGT1A1 result mean for chemotherapy?

Certain UGT1A1 gene patterns mean your body breaks down the chemotherapy drug Irinotecan more slowly, which can lead to a buildup of the drug and more severe side effects like low blood cell counts or diarrhea. This doesn't mean you can't receive the treatment, but it does mean dosing may need to be adjusted. This information is meant to be shared with your treatment team before chemotherapy begins.

How often should I retest for this?

Since this is a genetic test, your UGT1A1 pattern doesn't change over time, so you generally only need to take this test once in your lifetime. There's no need to repeat it unless there's a specific reason to confirm results, such as a lab error or conflicting prior test. Once you have your results, you can keep them on file and reference them whenever they're relevant, including for future medical situations.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

UGT1A1 Gene Test - Gilbert Syndrome & Chemo Safety

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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