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Genetic TTR test for families with hereditary amyloidosis or nerve/heart symptoms

TTR Gene Test for Hereditary Amyloidosis Risk

TTR DNA Sequence Testing

  • Screen for inherited nerve disease risk
  • Detect gene changes linked amyloidosis
  • Assess family history heart risk
$5507
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing unexplained nerve pain, numbness, heart problems, or you have a family history of a condition called hereditary transthyretin amyloidosis. It looks at your genes to see if you carry a change that can cause protein buildup in your nerves, heart, or other organs over time. Many people take this test because a relative was diagnosed with a TTR-related condition and they want to understand their own risk.

What's included in this test?

This test looks specifically at the TTR gene to check for sequence variants, which are small changes in your DNA that can affect how a protein called transthyretin behaves in your body. Finding a variant matters because certain changes are linked to a condition where this protein misfolds and builds up in tissues like the heart and nerves, so knowing your gene status can help you and your family plan ahead.

What happens after I get my results?

Your results will show up in your online account with a clear explanation of what a normal versus a variant result means for the TTR gene. If a variant is found, practical next steps include sharing the report with family members who may also want to get tested and watching for early symptoms like tingling, numbness, or shortness of breath so you can act quickly if they appear. You can download a standard lab report anytime from your account, and since this is a one-time genetic result, there's no need for retesting, though you can keep it saved and track any related follow-up tests over time using the trends feature.

How can I naturally support healthy nerve and heart function?
While you can't change your genes, you can support your nerves and heart with simple daily habits. Eating a balanced diet rich in omega-3 fats, staying physically active, limiting alcohol, and managing blood pressure all help protect nerve and heart tissue. Regular check-ins on symptoms like numbness, fatigue, or swelling can also help you catch changes early.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification once your report is available in your account, so there's no need to call and check. Because this is a detailed genetic test, it takes a bit longer than routine blood work.
Who should consider this test?
This test is a good fit if you have a close relative diagnosed with hereditary transthyretin amyloidosis or a related nerve or heart condition. It's also worth considering if you have unexplained symptoms like numbness, tingling, irregular heartbeat, or heart failure with no clear cause. People planning a family who want to understand inherited health risks may also find this test useful.
What symptoms indicate I may need this test?
Common signs linked to TTR-related conditions include numbness or tingling in the hands and feet, unexplained weight loss, carpal tunnel syndrome in both hands, irregular heartbeat, and shortness of breath or swelling from heart problems. These symptoms often develop slowly over years, so many people don't connect them until a family member is diagnosed. If you notice a combination of these along with a family history, this test can help clarify the cause.
What does a positive variant result mean?
A positive result means you carry a change in the TTR gene that's associated with hereditary transthyretin amyloidosis, a condition where a protein builds up in tissues like your heart and nerves. It doesn't mean you currently have symptoms or will definitely develop the condition, but it does mean you should watch closely for early signs and consider testing close family members. Simple steps like staying active, eating heart-healthy foods, and getting periodic symptom check-ins can help you stay ahead of any changes.
What causes TTR gene variants?
TTR gene variants are inherited, meaning they're passed down from a parent to a child, and they've been present since birth. They aren't caused by lifestyle, diet, or environment. If a variant runs in your family, each child of a carrier has roughly a 50% chance of inheriting it.
What should I do if my results show a variant?
If your results show a TTR variant, start by keeping a record of any new symptoms like numbness, fatigue, or heart palpitations so you can act early if they appear. Share your results with close biological relatives, since they may want to get tested too. Seek medical care promptly if you develop concerning symptoms like chest pain, severe swelling, or difficulty breathing.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
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Demo results
TTR Gene Sequence Variant Negative
Demo results
Negative (No Variant Detected) Positive (Variant Detected)
Negative

What this means

A negative result means no disease-associated sequence variant was found in your TTR gene. This suggests a lower genetic risk for hereditary transthyretin amyloidosis, though it doesn't rule out other causes of nerve or heart symptoms. If you still have symptoms, other health factors may be involved.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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TTR Gene Test for Hereditary Amyloidosis Risk

  • Screen for inherited nerve disease risk
  • Detect gene changes linked amyloidosis
  • Assess family history heart risk
$5507
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.