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Syphilis antibody test confirming treponemal infection after a positive screening result

Syphilis Confirmatory Antibody Blood Test

Treponema pallidum Antibody, Immunoassay

  • Confirm a positive syphilis screening result
  • Detect true syphilis antibody infection status
  • Screen for false positive test results
$56
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're following up on a positive syphilis screening result and need confirmation before drawing any conclusions. It helps if you have already had a non-treponemal test (like an RPR) come back positive and want to know whether it truly reflects a syphilis infection or a false alarm. It's a confirmation step, not a first-line screening test on its own.

What happens after I get my results?

Your results will show up in your account along with a plain-language explanation of what a positive or negative reading means. If your result confirms syphilis antibodies, the next step is prompt treatment and retesting after treatment to confirm the infection has cleared. If results are negative, it likely means your earlier positive screening was a false positive, though your results report explains any situations where retesting is recommended. You can download the full lab report anytime and track any future related tests over time using the trends feature.

Who should consider this test?

Anyone who has already received a positive result on a non-treponemal syphilis screening test (such as RPR or VDRL) should consider this confirmatory test. It's also useful for people who want a more specific check after an ambiguous or borderline screening result. This test is not meant to be the first test you take if you've never been screened for syphilis before.

What symptoms indicate I may need this test?
You may need this test if you've noticed sores, rashes, or unusual skin changes after a possible exposure, especially if you've already had a positive initial syphilis screen. Other reasons include a partner testing positive for syphilis or a routine screening coming back positive during pregnancy or a regular checkup. Because early syphilis symptoms can be mild or go unnoticed, many people only find out after a screening test flags a concern.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification as soon as your results are posted to your secure online account. If you need results sooner for treatment planning, check your order confirmation for any expedited options.
What is syphilis and why does confirmatory testing matter?
Syphilis is a bacterial infection spread through sexual contact that can cause serious health problems if left untreated. Because the initial screening test (non-treponemal) can sometimes give false positives from unrelated conditions, this antibody test specifically checks for antibodies made in response to the actual syphilis bacteria. Confirming the diagnosis this way helps avoid unnecessary treatment for a false alarm, or ensures you get treated promptly if the infection is real.
What does a positive result mean?
A positive result means your body has antibodies against the syphilis bacteria, which usually confirms a current or past infection. This antibody typically stays detectable for life, even after successful treatment, so a positive result along with symptoms or a recent exposure usually means treatment is needed now. Prompt treatment is important to prevent the infection from progressing and to avoid spreading it to others.
What does a negative result mean?
A negative result means no syphilis antibodies were found, which usually means your earlier positive screening test was a false positive. False positives can happen due to other infections, autoimmune conditions, or even pregnancy. If you still have symptoms or ongoing concerns, retesting after a few weeks can help rule out an infection caught too early to detect.
How often should I retest?
If your results confirm syphilis and you complete treatment, retesting every few months (commonly at 6 and 12 months) is recommended to confirm the treatment worked. If you're sexually active with new or multiple partners, annual screening is a reasonable habit regardless of past results. Your results report will note if your specific case suggests a different retest timeline.
What should I do if my results are abnormal?
If your result confirms syphilis antibodies, treatment with antibiotics is the standard next step and should happen as soon as possible. Avoid sexual contact until treatment is complete and you've been told it's safe to resume. Let recent sexual partners know so they can get tested too, since syphilis can spread even when symptoms aren't obvious.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Treponema pallidum Antibody Negative
Demo results
Negative (Normal) Positive (Antibodies Detected)
Negative

What this means

A negative result means no syphilis antibodies were detected, suggesting your earlier positive screening test was likely a false positive. This is generally a reassuring result, especially if you have no symptoms.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Syphilis Confirmatory Antibody Blood Test

  • Confirm a positive syphilis screening result
  • Detect true syphilis antibody infection status
  • Screen for false positive test results
$56
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.