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TPO Antibody Test for Autoimmune Thyroid Disease
TPO Antibody Endpoint
3,573 reviews
Detect autoimmune thyroid disease early
Screen for Hashimoto's and Graves' risk
Monitor immune-related thyroid problems
$149
CLIA-certified labs
First results as soon as overnight*
All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified
Prescription & all lab fees included
Go directly to the lab, no extra fees
Doctor's guidance included
Easy to understand results
Fast & convenient
Lab visit as quick as 10 mins in & out
Many results come back overnight *
90-day money back guarantee
Save time & skip the doctor’s office
Lab visit as quick as 10 minutes
Results explained, with clear next steps
LegitScript certified
No questions asked refunds
The price you see is the price you pay
Prescription & all lab fees included
Go directly to the lab, no extra fees
Doctor's guidance included
Easy to understand results
Fast & convenient
Lab visit as quick as 10 mins in & out
All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified
What's this test for?
This test is ideal if you're experiencing symptoms like unexplained weight changes, fatigue, hair loss, or mood swings that could point to a thyroid problem. It's also useful if you have a family history of autoimmune thyroid disease or other autoimmune conditions like type 1 diabetes. Checking for TPO antibodies helps identify whether your immune system is attacking your thyroid gland, which is a common cause of thyroid dysfunction.
What's included in this test?
This test measures thyroid peroxidase (TPO) antibodies, which are markers your immune system produces when it mistakenly targets your thyroid gland. Elevated TPO antibodies matter because they're one of the earliest signs of autoimmune thyroid conditions, often showing up before other thyroid hormone levels become abnormal. Catching this early can help you understand the root cause of thyroid symptoms rather than just treating the surface-level signs.
What happens after I get my results?
Your results will show up in your account along with an explanation of the normal range so you can see exactly where you stand. If your antibody levels are elevated, next steps usually involve tracking your thyroid function over time and making supportive lifestyle changes, such as reducing inflammatory foods and managing stress. You can download a standard lab report directly from your account for your records, and use the trends feature to monitor changes if you retest in the future. If a result looks dangerously abnormal alongside severe symptoms, seek medical care right away.
How can I naturally support thyroid health?
Eating a balanced diet with adequate iodine, selenium, and zinc can support normal thyroid function, and foods like Brazil nuts, fish, and eggs are good natural sources. Managing stress through sleep, exercise, and relaxation techniques can also help since chronic stress affects immune and hormone balance. Reducing exposure to inflammatory foods, like excess sugar and processed items, may help calm an overactive immune response. These steps support overall thyroid health but don't replace monitoring your antibody levels over time.
When will I get my results?
Results for this test are typically available within about 7 days of your sample being processed at the lab. You'll receive a notification once your results are ready to view in your account. This timeframe allows the lab to accurately measure antibody levels using specialized testing methods.
Who should consider this test?
This test is a good fit for anyone with symptoms of thyroid imbalance, such as fatigue, weight changes, hair thinning, or feeling unusually cold or hot. It's also worth considering if you have a personal or family history of autoimmune conditions like Hashimoto's, Graves' disease, or type 1 diabetes. People already diagnosed with a thyroid condition may also use this test to better understand the underlying cause.
What symptoms indicate I may need this test?
Common symptoms that suggest you might benefit from this test include persistent fatigue, unexplained weight gain or loss, hair loss, dry skin, feeling cold or overheated easily, and mood changes like anxiety or depression. Some people also notice swelling in the neck area or irregular heart rate. If these symptoms have been ongoing without a clear explanation, checking your thyroid antibodies can help identify an autoimmune cause.
What does high TPO antibody mean?
A high TPO antibody level usually means your immune system is attacking your thyroid gland, which is a hallmark of autoimmune thyroid conditions like Hashimoto's thyroiditis or Graves' disease. This doesn't always cause symptoms right away, but it can signal an increased risk of developing thyroid dysfunction over time. Simple lifestyle changes, like reducing inflammation through diet and stress management, along with regular retesting, can help you keep track of how things progress.
What causes high TPO antibodies?
High TPO antibodies are typically caused by an autoimmune response, where the immune system mistakenly identifies thyroid tissue as a threat. This can be influenced by genetics, other autoimmune conditions, chronic stress, and sometimes environmental triggers like infections. Family history plays a significant role, so if autoimmune thyroid disease runs in your family, you may be more likely to develop elevated antibodies.
How often should I retest?
If your levels are elevated or borderline, retesting every 6 to 12 months can help you track whether your antibody levels are rising, falling, or staying stable. If your results are normal but you have risk factors like family history or ongoing symptoms, an annual check can be a reasonable approach. Using the trends feature in your account makes it easy to see these changes over time.
How’s this work?
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In the test options, use the filters or search box to narrow your choices and find the test you want.
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When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want.
If you’re not sure which test to get, we can lend a hand in finding the right option.
Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.
Just reach out to us via text at 754-799-7833 or shoot us an email at
[email protected]. Remember to include your order number and let us know the correct information you’d like to update.
Our awesome team will jump right in and make sure everything is sorted out and accurate for you.
There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.
Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.
Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.
This policy applies to all insurance companies, including federal health insurance programs like Medicare.
You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached!
You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).
Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.
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Demo results
Thyroid Peroxidase (TPO) Antibody45 IU/mL
Demo results
Normal (0-34 IU/mL)Elevated (>34 IU/mL)
45 IU/mL
What this means
Your TPO antibody level is above the normal range, suggesting your immune system may be targeting your thyroid gland. This is often an early sign of autoimmune thyroid conditions like Hashimoto's thyroiditis, even if your thyroid hormone levels are still normal.
Recommended actions
Reduce inflammatory foods like sugar and processed snacks
Add selenium and zinc-rich foods to your diet
Manage stress through better sleep and relaxation habits
Retest in 6-12 months to track antibody trends
* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
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Order your testSave a trip to the doctor. Your results will come with clear, friendly explanations.Takes 2 minutes
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Find a lab near you
Search Quest Diagnostics and LabCorp locations available through Private MD Labs.
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