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This test is ideal if you're concerned about your heart health, especially if you have moderate or high risk factors for cardiovascular disease. It measures TMAO, a chemical produced by gut bacteria when you eat certain foods like red meat, eggs, and fish, which has been linked to increased risk of heart attacks and strokes. Many people use this test to better understand their cardiovascular risk beyond traditional cholesterol testing, particularly if they have a family history of heart disease or other risk factors.
You should fast overnight before your blood draw, which means no food or drinks except water for 8-12 hours. It's also important to avoid eating fish and other seafood the day before your test, as these foods can temporarily elevate TMAO levels and may lead to inaccurate results. Take your test in the morning after fasting for best results.
This test measures TMAO (Trimethylamine N-oxide), a compound produced when gut bacteria break down certain nutrients found in red meat, eggs, and seafood. Elevated TMAO levels have been associated with increased risk of heart attacks, strokes, and other major cardiovascular events, making it a valuable marker for assessing heart disease risk beyond traditional cholesterol and lipid panels.
What this means
Your TMAO level is elevated, which may indicate increased cardiovascular risk. Higher TMAO levels have been associated with greater risk of heart attacks, strokes, and other cardiac events. This suggests your gut bacteria may be producing excess TMAO from your current diet, particularly from red meat, eggs, or high-fat animal products.
Recommended actions
Reduce consumption of red meat, egg yolks, and high-fat dairy products
Increase plant-based foods like fruits, vegetables, whole grains, and legumes
Consider taking probiotics or eating fermented foods to support healthier gut bacteria
Retest in 3-6 months after implementing dietary changes
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