What's this test for?

This test is ideal if you're experiencing recurrent blood clots, had a clot at a young age, or have a strong family history of venous thromboembolism (VTE). It's also useful if you developed a clot in an unusual location, like the brain, or if previous clotting tests showed low activated protein C resistance. Knowing whether you carry these inherited gene variants can help explain why clotting happened and guide future prevention decisions.

What's included in this test?

This test looks at two specific gene changes that are the most common inherited causes of abnormal blood clotting. It checks for a variant in the factor V gene, which makes clotting factor V harder for the body to break down, and a variant in the prothrombin (factor II) gene, which can raise clotting factor levels. If you carry one copy of the factor V Leiden variant, the test automatically checks for a related variant called R2, since having both together further raises clot risk.

What happens after I get my results?

Your results will show up in your account with a clear explanation of what each finding means, including whether you carry the factor V Leiden or prothrombin gene variants. If you're positive for factor V Leiden as a heterozygous carrier, the report will also include your R2 variant status, which can affect your overall clot risk. Because this is a one-time genetic result, retesting isn't needed, but you can keep the report on file and revisit it anytime through your account's trends feature. A downloadable lab report is always available if you need to share your results or keep them for personal records.

How can I naturally support healthy blood clotting risk?

While you can't change genetic variants, you can lower your overall clotting risk through lifestyle choices. Staying active, maintaining a healthy weight, avoiding long periods of sitting or immobility (especially on flights), and staying well-hydrated all help support healthy blood flow. Avoiding smoking and limiting estrogen-containing medications, when possible, are also important, especially if you carry one of these gene variants.

When will I get my results?

Results are typically ready within about 7 days of your blood draw. Because this involves genetic analysis, including the reflex R2 testing when applicable, it takes a bit longer than routine bloodwork. You'll be notified as soon as your results are available in your account.

Who should consider this test?

This test is worth considering if you've had a blood clot before age 50, a clot in an unusual location, recurrent clots, or if close family members have a history of clotting disorders. It may also be useful if you're planning pregnancy or hormone therapy and have a family history of clotting problems. It is not typically recommended for routine screening in people without personal or family clotting history.

What symptoms indicate I may need this test?

Symptoms like leg swelling, pain, warmth, or redness (signs of a possible deep vein clot), sudden shortness of breath or chest pain (which can signal a lung clot), or repeated miscarriages can be signs of an underlying clotting disorder. If you or a close family member has experienced any of these, especially at a young age, this test may help identify a genetic cause. Seek emergency medical care immediately if you have symptoms of a lung clot, like sudden severe shortness of breath or chest pain.

What does a positive factor V Leiden result mean?

A positive result means you carry a gene variant that makes it harder for your body to naturally break down a clotting protein, which raises your risk of developing blood clots. Having one copy (heterozygous) increases risk 6 to 8 times, while having two copies (homozygous) raises it up to 80 times compared to people without the variant. This doesn't mean you will definitely get a clot, but it's helpful information for making informed choices about activity, medications, and travel precautions.

What causes these clotting gene variants to be present?

These gene variants are inherited from one or both parents at birth, they are not caused by lifestyle or diet. Factor V Leiden and the prothrombin gene variant are both passed down and are most common in people of White/European ancestry. Since they're inherited, family members may want to consider testing if you test positive.

What should I do if my results are positive?

If your results show one of these variants, take extra precautions during high-risk situations like long flights, surgery, or pregnancy, since these can further raise clot risk. Talk to family members about testing, since these variants run in families. If you ever experience sudden leg swelling, chest pain, or shortness of breath, seek emergency medical care right away, as these can be signs of a dangerous clot.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Thrombophilia Test - Inherited Blood Clot Risk

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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