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Autoimmune antibody panel for adults with scleroderma or Raynaud's symptoms

Scleroderma Antibody Panel — 12 Autoimmune Markers

Systemic Sclerosis (Scleroderma) 12 Antibodies Panel 2

  • Screen for scleroderma-related antibodies
  • Check skin tightening and Raynaud's causes
  • Monitor autoimmune organ complication risks
$6025
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
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Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you're experiencing skin thickening, tightening or hardening, unexplained Raynaud's phenomenon (fingers turning white or blue in the cold), joint pain, difficulty swallowing, or shortness of breath. These can be signs of systemic sclerosis (scleroderma), an autoimmune condition that affects the skin, blood vessels, and internal organs. This panel checks for a wide range of antibodies linked to scleroderma to help you understand what may be causing your symptoms.

What's included in this test?

This panel measures several different antibodies that are each linked to specific patterns of scleroderma, such as limited skin disease, diffuse skin disease, or overlap with other autoimmune muscle conditions. Testing multiple antibodies together matters because different antibodies point to different disease patterns, organ risks, and outlooks, which gives a fuller picture than checking just one marker alone.

What happens after I get my results?

Your results will appear in your account with each antibody's normal range clearly explained. If any antibodies come back positive, next steps typically include tracking your symptoms closely, retesting periodically to watch for changes, and seeking medical care promptly if you notice worsening skin changes, breathing problems, or severe Raynaud's episodes. You can download a standard lab report from your account at any time, and the trends feature lets you track your antibody levels over time if you retest in the future.

How can I naturally support healthy circulation and skin?
Staying warm and avoiding cold exposure can help reduce Raynaud's flare-ups that are common with scleroderma-related conditions. Gentle regular movement, staying hydrated, and moisturizing skin daily can help with circulation and skin comfort. Avoiding smoking and limiting caffeine may also reduce blood vessel spasms in the fingers and toes.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification as soon as they're available in your account, so there's no need to call or check in manually.
Who should consider this test?
This test is a good option for people with symptoms like skin tightening, persistent Raynaud's phenomenon, unexplained joint stiffness, or difficulty swallowing that hasn't been explained by another cause. It's also useful for people who already have a scleroderma diagnosis and want a fuller picture of which antibodies are present. Anyone with a close family history of autoimmune disease and new unexplained symptoms may also want to consider it.
What symptoms indicate I may need this test?
Common symptoms include skin that feels thick, tight, or shiny, fingers or toes that turn white or blue in cold temperatures, joint pain or stiffness, trouble swallowing, and shortness of breath. Some people also notice small white calcium deposits under the skin or visible small blood vessels near the surface of the skin. If you're noticing a combination of these symptoms, this panel can help identify an underlying cause.
What is systemic sclerosis and why does it matter?
Systemic sclerosis, also called scleroderma, is an autoimmune condition where the body produces antibodies that attack its own tissue, leading to thickened skin and scarring in internal organs like the lungs, heart, or kidneys. It matters because catching it early can help you manage symptoms and monitor organ involvement before it becomes more serious. Different antibody patterns are linked to different levels of organ risk, so knowing your antibody profile helps guide what to watch for.
How often should I retest?
If your results are negative and you're not having symptoms, retesting isn't usually necessary unless new symptoms appear. If you have a positive result or an existing scleroderma diagnosis, retesting every 6 to 12 months can help track how your condition may be changing over time. Any new or worsening symptoms are also a good reason to consider retesting sooner.
What should I do if my results are abnormal?
If one or more antibodies come back positive, start by tracking your symptoms, including skin changes, joint pain, swallowing issues, or breathing changes. Keep a record of when symptoms flare and share this information if you seek medical care. If you notice sudden shortness of breath, chest pain, or rapidly worsening skin or finger color changes, seek medical care right away.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
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US-licensed doctors have your back if things get unclear.
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Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
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Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Anti-Centromere (CENP) Antibody Negative
Demo results
Negative Positive
Negative

What this means

A negative result means no anti-centromere antibodies were detected, which makes limited cutaneous scleroderma (CREST syndrome) less likely. A positive result would suggest an autoimmune process affecting the skin and blood vessels that may need closer monitoring.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Scleroderma Antibody Panel — 12 Autoimmune Markers

  • Screen for scleroderma-related antibodies
  • Check skin tightening and Raynaud's causes
  • Monitor autoimmune organ complication risks
$6025
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.