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Lupus disease activity panel for patients managing autoimmune flare symptoms

Lupus (SLE) Disease Activity Blood Test

Systemic Lupus Erythematosus (SLE), Disease Activity Panel

  • Track lupus flare activity levels
  • Screen for immune system inflammation
  • Monitor kidney health over time
$754
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you're experiencing joint pain, unexplained fatigue, skin rashes, or fevers that come and go without a clear cause. It's also useful if you've already been diagnosed with lupus and need to track how active the disease currently is. Many people use this panel to see whether their symptoms line up with a flare or with inflammation building up in the body.

What's included in this test?

This panel combines markers that reflect immune system activity and inflammation, since lupus is driven by the immune system mistakenly attacking healthy tissue. Some markers show how active the disease is right now, while others help spot strain on organs like the kidneys that lupus can affect over time. Looking at these together gives a fuller picture of disease activity than any single marker alone.

What happens after I get my results?

Your results will be available in your account, with each value shown alongside its normal range and a plain-language explanation of what it means. Depending on what shows up, next steps might include adjusting rest, stress, and sun exposure habits, or retesting in a few weeks to see if a value is trending up or down. If any result comes back at a dangerous level, the report will flag it so you know to seek medical care right away. You can also use the trends feature to watch how your values change over time, which is especially helpful for a condition like lupus that flares and settles.

How can I naturally support immune balance during a lupus flare?
Getting consistent sleep, minimizing sun exposure, and managing stress through activities like gentle yoga or walking can help reduce flare triggers. An anti-inflammatory eating pattern with plenty of vegetables, fatty fish, and less processed food may also ease symptoms for some people. Avoiding smoking and limiting alcohol supports overall immune health as well. These habits work alongside, not instead of, monitoring your lab values regularly.
When will I get my results?
Lab results for this panel are typically ready within about 7 days of your sample being processed. You'll get a notification as soon as they're posted to your account so you don't need to keep checking back. If a result looks urgent, the report will make that clear right away.
Who should consider this test?
People already diagnosed with lupus who want to check whether the disease is currently active are the main audience for this panel. It's also worth considering if you have ongoing symptoms like joint swelling, rashes, or fatigue and want more information before deciding on next steps. Anyone tracking how well their current lifestyle changes are working can use this test to see measurable progress.
What symptoms indicate I may need this test?
Common signs include joint pain or stiffness, a butterfly-shaped facial rash, extreme fatigue that doesn't improve with rest, low-grade fevers, and sensitivity to sunlight. Hair loss, mouth sores, and swelling in the hands or feet can also be signs worth checking. If these symptoms come and go in cycles, that pattern itself is a common clue.
What is lupus disease activity and why does it matter?
Lupus disease activity refers to how much inflammation and immune system attack is happening in your body at a given time, rather than whether you have lupus at all. It matters because activity levels rise and fall, and catching a rise early can help you make changes before symptoms get worse or organs are affected. Tracking activity over time is more useful than a single one-time check.
How often should I retest?
Many people with lupus retest every few months, or sooner if new symptoms appear or existing ones get worse. If you're in the middle of a flare, more frequent checks can help you and your care routine understand whether things are improving. During stable periods, testing less often is usually reasonable.
What should I do if my results are abnormal?
Start by reviewing which specific values are outside the normal range, since the report explains what each one means in context. Simple steps like increasing rest, reducing sun exposure, and lowering stress can help with mild changes, while significantly abnormal results calling for urgent attention should prompt you to seek medical care. Retesting after making changes is a good way to see if your numbers are moving in the right direction.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Complement C3 78 mg/dL
Demo results
Low (<90 mg/dL) Normal (90-180 mg/dL) High (>180 mg/dL)
78 mg/dL

What this means

Your Complement C3 is lower than normal, which can happen when the immune system is actively using up these proteins during a lupus flare. Low C3 often shows up alongside other signs of increased disease activity. This value is best understood alongside your other markers rather than on its own.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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Lupus (SLE) Disease Activity Blood Test

  • Track lupus flare activity levels
  • Screen for immune system inflammation
  • Monitor kidney health over time
$754
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.