What's this test for?

This test is ideal if you're experiencing a sore, ulcer, or lesion that could be syphilis and you need a fast, direct answer. It's especially useful if you've already had a syphilis antibody (serology) test that came back negative but your symptoms still look like syphilis. It's also used to help evaluate newborns whose mothers had syphilis during pregnancy.

What's included in this test?

This test looks directly for the genetic material (DNA) of the bacteria that causes syphilis, Treponema pallidum, rather than looking for antibodies your body makes in response to it. This matters because it can catch an active infection very early, sometimes before antibody tests turn positive, and it can clarify confusing cases where symptoms and antibody results don't match.

What happens after I get my results?

Your result will appear in your account as either DNA detected or not detected, along with a plain-language explanation of what that means. If the result is positive, the next step is usually to seek care right away since syphilis is treatable but needs prompt action; if it's negative but your symptoms continue, retesting or a follow-up serology test is a reasonable next step. You can download the standard lab report from your account at any time, and if you test again in the future, you can track results over time using the trends feature.

How can I naturally support recovery while waiting on results?

While no natural remedy treats or cures syphilis, you can support your body by avoiding sexual contact until you know your status to prevent spreading infection, keeping any sores clean and dry, and eating a balanced diet to support your immune system. Avoiding alcohol and getting enough sleep can also help your body handle any infection more effectively. These steps are not a substitute for treatment if the result comes back positive.

When will I get my results?

Results are typically ready within about 7 days of your sample being received at the lab. Because this is a specialized molecular (PCR) test, it takes a bit longer than a basic blood test, but you'll be notified as soon as your results are posted to your account.

Who should consider this test?

This test is a good fit for people with an active sore or lesion suspicious for syphilis, especially if a standard antibody test came back negative despite clear symptoms. It's also considered for newborns being evaluated for congenital syphilis. It is not meant to replace routine STI screening for people without symptoms.

What symptoms indicate I may need this test?

Watch for a firm, usually painless sore (called a chancre) on the genitals, anus, or mouth, which is the classic early sign of syphilis. Swollen lymph nodes near the sore can also occur. If you notice a new sore after unprotected sexual contact, especially one that doesn't hurt, it's worth getting checked.

What does a positive (DNA detected) result mean?

A positive result means the bacteria's genetic material was found in your sample, which strongly suggests an active syphilis infection. This is considered a reliable sign of infection, especially during the earliest stage when antibody tests can still be negative. Prompt treatment is important to prevent the infection from progressing to later, more serious stages.

What does a negative result mean, and could it still be syphilis?

A negative result means no bacterial DNA was found in your specific sample, but this does not completely rule out syphilis. The bacteria can be missed if the sample was taken from a lesion that's healing, or if the infection has moved past the stage where this test works best. If symptoms persist, a follow-up antibody (serologic) test is recommended.

How often should I retest?

If your result is negative but you still have symptoms or ongoing exposure risk, retesting within a week or two, or pairing this test with serology, is a reasonable approach. If you've been treated for a positive result, standard follow-up uses antibody blood tests rather than this DNA test to confirm the infection has cleared. Regular STI screening every 3-6 months is generally recommended for anyone with new or multiple partners.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Syphilis PCR DNA Test - Fast Lesion Detection

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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