What's this test for?

This test is ideal if you're already undergoing a lymphoma workup and your care team needs more specific information about a tissue or biopsy sample. SOX-11 IHC (immunohistochemistry) helps distinguish mantle cell lymphoma, including rare forms that don't show up on standard markers, from other lymphomas that can look similar under the microscope. It's typically ordered as a follow-up test on existing tissue samples rather than as a first-line screening test.

What's included in this test?

This test measures a single, highly specific marker called SOX-11 using a technique called immunohistochemistry (IHC), which stains tissue samples to show where a specific protein is present. SOX-11 matters because it shows up in almost all cases of mantle cell lymphoma but not in similar-looking conditions, making it a powerful tool for telling these conditions apart. The interpretation that comes with your result explains what the staining pattern found in your sample means.

What happens after I get my results?

Your results will be available in your account along with an explanation of what the SOX-11 staining pattern means for your sample. Because this is a specialized pathology test tied to a specific tissue sample, next steps usually involve reviewing the interpretation alongside any other biomarker tests run on the same sample rather than a simple retest. The full lab report is downloadable directly from your account at any time. If you have ongoing monitoring needs, you can track related results over time using the trends feature.

How can I naturally support my immune and lymphatic health?

While this test result itself isn't something you can influence through lifestyle changes, supporting your overall immune and lymphatic health is always a good idea. Staying hydrated, eating a diet rich in fruits, vegetables, and lean protein, staying physically active, and getting enough sleep all help your body's natural defenses function well. Avoiding excess alcohol and not smoking are also two of the most impactful habits for long-term immune health.

When will I get my results?

Results for this test are typically ready within about 7 days of your sample being processed at the lab. Because this is a specialized interpretive pathology test, it can occasionally take a bit longer than routine bloodwork. You'll receive a notification as soon as your results are posted to your account.

Who should consider this test?

This test is generally considered by people who already have a tissue biopsy sample being evaluated for a possible lymphoma, particularly when a diagnosis of mantle cell lymphoma is being considered or needs to be distinguished from similar conditions. It's not a general screening test for the public and is most useful when ordered alongside other pathology work already in progress. If you're unsure whether this specific test applies to your situation, review the details with whoever is coordinating your existing workup.

What is mantle cell lymphoma and why does testing for it matter?

Mantle cell lymphoma is a type of blood cancer that starts in the lymph nodes and can sometimes be tricky to diagnose because it looks similar to other lymphomas under a microscope. Getting the diagnosis right matters because treatment approaches differ between lymphoma types. SOX-11 is a helpful marker precisely because it's present in almost all mantle cell lymphoma cases, including rarer subtypes, while staying absent in common lookalike conditions.

What does a positive SOX-11 result mean?

A positive SOX-11 result means the protein was found in the nucleus of the cells in your tissue sample, which is a pattern strongly associated with mantle cell lymphoma. This finding is usually interpreted together with other tests done on the same sample rather than on its own. The full written interpretation included with your report explains what this specific pattern means in the context of your case.

What does a negative SOX-11 result mean?

A negative SOX-11 result means the marker wasn't detected in the sample, which makes mantle cell lymphoma less likely and points toward other possible diagnoses like certain other lymphomas. As with a positive result, this is typically interpreted alongside other pathology findings from the same sample. The report will walk through what a negative finding suggests for your specific case.

What should I do if my results are unclear or concerning?

If your results raise questions or seem concerning, the best next step is to have the full pathology report reviewed together with any other tests done on the same tissue sample, since SOX-11 is rarely interpreted in isolation. Keep a copy of your downloadable report so it can be referenced alongside future testing. If you experience any new or worsening symptoms in the meantime, seek medical care promptly.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

SOX-11 IHC Test - Mantle Cell Lymphoma Marker

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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