What's this test for?

This test is ideal if you're experiencing joint pain, unexplained rashes, fatigue, or other symptoms that might point to lupus. It looks for a specific antibody in your blood that is strongly linked to systemic lupus erythematosus (SLE), an autoimmune condition. It's especially useful if you've had unclear symptoms for a while and want a more specific answer than general screening tests provide.

What happens after I get my results?

Your results will show up in your account with the normal range clearly explained next to your value. If your result is positive, the report will explain what that means and suggest tracking your symptoms and retesting as part of ongoing monitoring; if a value looks concerning, the report will flag when to seek medical care right away. You can download a standard lab report anytime from your account, and the trends feature lets you compare this result to future tests over time.

Who should consider this test?

This test is a good fit for anyone with symptoms like joint pain, skin rashes, fatigue, or fever that haven't been explained by other causes. It's also useful if you've already had a positive general lupus screening test and want a more specific follow-up. Young African-American women, who have higher rates of this antibody with SLE, may find this test particularly relevant.

What symptoms indicate I may need this test?

Common symptoms linked to lupus include joint pain and swelling, a butterfly-shaped facial rash, unexplained fatigue, fever, and sensitivity to sunlight. Some people also notice hair loss, mouth sores, or chest pain when breathing deeply. If you've had several of these symptoms together for weeks or months, this test can help clarify what's going on.

When will I get my results?

Results are typically ready within about 7 days of your blood draw. Once processed, they'll be uploaded directly to your secure online account. You'll be able to view, download, and track them as soon as they're available.

What is Smith Antibody and why does it matter?

Smith Antibody, often called Sm antibody, is a marker your immune system sometimes produces when it mistakenly attacks your own body, a hallmark of autoimmune disease. It's considered highly specific for lupus, meaning a positive result strongly suggests SLE rather than another condition. Because it doesn't show up in everyone with lupus, it's often used alongside other tests to build a clearer picture.

What does a positive Sm Antibody result mean?

A positive result means this specific antibody was found in your blood, which is strongly associated with systemic lupus erythematosus. It doesn't automatically mean you have lupus, since other factors and symptoms matter too, but it raises the likelihood significantly. If you get a positive result along with symptoms like joint pain or rashes, it's a good idea to seek medical care to discuss next steps.

What causes a positive Sm Antibody result?

A positive result happens when your immune system produces antibodies that target proteins in your own cells, which is common in autoimmune conditions like lupus. Genetics, environmental triggers, and certain infections can all play a role in why this happens. It's not something caused by diet or lifestyle choices, so there's no quick fix to reverse it.

How often should I retest?

If your first result is negative but you still have symptoms, retesting every few months can help catch changes early. If you've tested positive, periodic retesting can help you and your care routine track how things are progressing over time. Your report will include guidance on a retest timeline based on your specific result.

What should I do if my results are abnormal?

If your result comes back positive, start by keeping a detailed log of your symptoms, including when they flare up and how severe they are. Reducing stress, getting enough sleep, and protecting your skin from sun exposure can help manage lupus-related symptoms. If you notice severe symptoms like chest pain, extreme fatigue, or swelling, seek medical care promptly.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Sm Antibody Test - Lupus Symptom Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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