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Syphilis Test - Private Screening & Diagnosis

RPR (Diagnosis) with Reflex to Titer and Treponema pallidum Antibody, IA

  • Detects syphilis infection in blood.
  • Confirms syphilis with additional tests.
  • Checks syphilis antibody levels.
$99
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

Sample health report with biomarker results, insights, and recommendations See what you get

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're sexually active and want to screen for syphilis, or if you've been exposed to someone with syphilis. It helps detect and confirm syphilis infection, which is important because early-stage syphilis often has mild or no symptoms but can cause serious health problems if left untreated. Many people use this test for routine sexual health screening, after unprotected sex, or when experiencing symptoms like unusual sores, rashes, or swollen lymph nodes.

How should I prepare for this test?

No special preparation is needed for this test. You don't need to fast, and you can take your regular medications. The blood sample can be collected at any time of day. Just arrive at the lab with your test order, and the blood draw typically takes just a few minutes.

What's included in this test?

Rpr (Dx) W/Refl Titer And Confirmatory Testing

This panel uses a two-step approach to accurately diagnose syphilis. It starts with an RPR screening test that detects antibodies your body produces in response to syphilis infection. If the RPR is positive, it automatically reflexes to additional confirmatory testing including titer levels (which measure infection severity) and Treponema pallidum antibody testing to verify the diagnosis and rule out false positives. This comprehensive approach provides both accurate diagnosis and information about disease activity.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your results mean for your sexual health and next steps. These notes include guidance on whether treatment is needed, how to prevent transmission, and when follow-up testing might be recommended. You'll also get the standard lab report and can track your results over time using our trends feature, which is especially helpful if you're monitoring treatment effectiveness or doing routine screening.
When will I get my results?
Most results are available within 1-3 business days after your blood sample is collected at the lab. If your initial screening is positive and reflex testing is needed, it may take an additional 1-2 days for the confirmatory tests. You'll receive an email notification when your results are ready to view securely online.
Who should consider getting this test?
Anyone who is sexually active should consider regular syphilis screening as part of routine sexual health care. This test is especially important if you've had unprotected sex, multiple partners, a new partner, or if a partner has tested positive for syphilis. It's also recommended for pregnant women, people with other STIs, and those experiencing symptoms like painless sores, unusual rashes, or flu-like symptoms.
What symptoms indicate I may need this test?
Early syphilis often causes painless sores (chancres) on the genitals, mouth, or rectum that appear 10-90 days after infection. Later symptoms may include skin rashes (especially on palms and soles), swollen lymph nodes, fever, fatigue, sore throat, or hair loss. However, many people have no noticeable symptoms at all, which is why routine screening is important if you're sexually active.
What does a positive RPR result mean?
A positive RPR indicates that antibodies associated with syphilis infection are present in your blood, suggesting you may have an active syphilis infection. This triggers automatic confirmatory testing with titer measurements and Treponema pallidum antibody tests to verify the diagnosis and assess infection severity. A positive confirmed result means you'll need antibiotic treatment, which is highly effective at curing syphilis, especially when caught early.
How is syphilis treated if my test is positive?
Syphilis is treated with antibiotics, most commonly penicillin injections. Early-stage syphilis typically requires a single dose, while later-stage infections may need multiple treatments. Treatment is highly effective and can cure the infection, though it cannot reverse damage already done to organs. Your doctor will provide specific treatment recommendations based on your test results and infection stage.
How can I protect myself from syphilis?
The most effective protection is using latex condoms correctly during every sexual encounter, though they don't provide complete protection since syphilis can spread through contact with sores outside the covered area. Limiting your number of sexual partners, being mutually monogamous with an uninfected partner, and getting regular STI screenings reduce your risk. Open communication with partners about sexual health and testing is also crucial for prevention.
How often should I get tested for syphilis?
If you're sexually active with multiple partners or new partners, annual syphilis screening is recommended, or every 3-6 months if you're at higher risk. After treatment for syphilis, follow-up testing is typically done at 6 and 12 months to ensure the infection has been cured. If you have potential exposure to syphilis, test immediately and again at 6 weeks and 3 months, as it can take time for antibodies to develop.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
    8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Syphilis Test - Private Screening & Diagnosis

  • Detects syphilis infection in blood.
  • Confirms syphilis with additional tests.
  • Checks syphilis antibody levels.
$99
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.