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RNP antibody test for detecting mixed connective tissue disease and autoimmune symptoms

RNP Antibody Test for Autoimmune Symptom Screening

RNP Antibody

  • Detect early autoimmune disease signs
  • Screen joint pain and fatigue causes
  • Monitor immune system health changes
$502
LegitScript certified merchant
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing joint pain, muscle weakness, swollen fingers, fatigue, or unexplained skin changes that could point to an autoimmune condition. It looks for RNP antibodies, which the body sometimes produces when the immune system mistakenly attacks its own tissues. This can help you understand whether an autoimmune disorder like Mixed Connective Tissue Disease may be behind your symptoms.

What happens after I get my results?

Your results will be available in your account, with each value's normal range explained in plain language so you know exactly what your number means. If your RNP antibody level comes back elevated, next steps typically include watching for new or worsening symptoms and considering a follow-up test to confirm the finding, while a normal result usually means no further action is needed unless symptoms continue. You can download a standard lab report from your account at any time, and the trends feature lets you track this marker over time if you retest in the future. If you have severe symptoms like difficulty breathing or extreme swelling, seek medical care right away.

What is Mixed Connective Tissue Disease and why does it matter?

Mixed Connective Tissue Disease is a condition where the immune system attacks healthy tissue, causing symptoms that can overlap with several other autoimmune disorders like lupus or scleroderma. It matters because catching it early can help you make lifestyle adjustments and monitor your health before symptoms become more serious. RNP antibodies are one of the key markers used to identify this condition.

How can I naturally support immune system balance?
Getting enough sleep, managing stress, and eating an anti-inflammatory diet rich in fruits, vegetables, and omega-3 fats can help support a balanced immune system. Regular, moderate exercise and avoiding smoking also play a role in reducing overall inflammation. These habits won't replace testing, but they're a good foundation while you monitor your results.
When will I get my results?
Results are typically ready within about 7 days of your lab visit. Once processed, they'll be uploaded directly to your secure online account, and you'll be notified as soon as they're available. You can log in anytime after that to view your report.
Who should consider this test?
This test is a good fit for anyone with ongoing joint pain, muscle weakness, unexplained fatigue, or skin symptoms like puffy fingers that haven't been explained by other causes. It's also useful if you have a family history of autoimmune disease and want to check your own risk. People already diagnosed with one autoimmune condition who develop new symptoms may also benefit from this test.
What symptoms indicate I may need this test?
Common symptoms linked to RNP antibodies include joint pain and stiffness, muscle weakness, swollen or puffy fingers, fatigue, and Raynaud's phenomenon (fingers turning white or blue in the cold). Some people also notice skin rashes or unexplained low-grade fevers. If several of these symptoms show up together, it may be worth checking your RNP antibody levels.
What does a high RNP antibody result mean?
A high or positive RNP antibody result suggests your immune system may be producing antibodies against your own tissue, which is commonly seen in Mixed Connective Tissue Disease. It doesn't automatically mean you have the condition, since these antibodies can sometimes appear without symptoms, but it's a signal worth paying attention to. Tracking your symptoms and considering a retest can help clarify what the result means for you.
How often should I retest?
If your first result is normal but you continue having symptoms, retesting in a few months can help catch changes early. If your result is elevated, your report will guide you on a reasonable retest window, often around 3 to 6 months, to monitor any changes. Retesting sooner makes sense if new symptoms develop.
What should I do if my results are abnormal?
If your RNP antibody result is elevated, start by tracking any symptoms you're having, like joint pain, fatigue, or skin changes, and note when they occur. Focus on anti-inflammatory lifestyle habits such as better sleep, stress management, and a balanced diet while you monitor things. Consider retesting after a few months to see if the level changes, and seek medical care promptly if symptoms become severe.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
RNP Antibody Negative
Demo results
Negative (Normal) Positive (Elevated)
Negative

What this means

A negative result means no significant RNP antibodies were detected in your blood, which is the expected finding for most healthy people. This makes Mixed Connective Tissue Disease less likely to be the cause of your symptoms. If symptoms persist, other causes may need to be explored.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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RNP Antibody Test for Autoimmune Symptom Screening

  • Detect early autoimmune disease signs
  • Screen joint pain and fatigue causes
  • Monitor immune system health changes
$502
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.