What's this test for?

This test is ideal if you're experiencing unusual nerve symptoms like tingling, numbness, muscle stiffness, or unexplained muscle spasms. It's also useful if you've been diagnosed with certain cancers and your care has raised concerns about a related nerve or muscle condition. The test looks for a specific antibody that's linked to rare neurological conditions such as Stiff-Person syndrome and paraneoplastic nerve disorders.

What happens after I get my results?

Your results will show up in your online account along with a clear explanation of what's considered a normal versus positive range for this antibody. If your result comes back positive, the report will explain what that may mean, and severe or worsening symptoms should prompt immediate medical attention. You can download a standard lab report anytime from your account, and if you retest in the future, the trends feature lets you compare results side by side to track any changes.

What symptoms indicate I may need this test?

Symptoms that might point to needing this test include muscle stiffness or rigidity, painful muscle spasms, numbness or tingling in your hands and feet, balance problems, or unexplained weakness. People with a known cancer diagnosis who develop new neurological symptoms are also often candidates. These symptoms can have many causes, so this test helps narrow down whether an autoimmune antibody reaction is involved.

How can I naturally support nerve and muscle health?

While this antibody condition itself needs targeted attention, everyday habits can help support your nervous system overall. Getting regular gentle movement or stretching, eating a balanced diet rich in B vitamins and antioxidants, managing stress, and getting consistent sleep all support nerve function. These steps won't resolve an autoimmune antibody issue on their own, but they can help you feel your best while you sort out next steps.

When will I get my results?

Results for this test are typically ready within about 7 days after your sample is collected. This is a specialized antibody test, so it takes a bit longer to process than routine bloodwork. You'll get a notification as soon as your results are posted to your account.

Who should consider this test?

People with unexplained sensory neuropathy, muscle stiffness, or spasms that haven't been explained by other testing should consider this test. It's also relevant for those with a history of certain cancers who develop new or unusual neurological symptoms, since this antibody is sometimes linked to paraneoplastic conditions. If you've already been told you might have a condition like Stiff-Person syndrome or limbic encephalitis, this test can help confirm or monitor that diagnosis.

What is the Amphiphysin antibody and why does it matter?

The Amphiphysin antibody is a protein your immune system sometimes produces by mistake, and it can attack nerve tissue. Its presence is linked to rare conditions like Stiff-Person syndrome, certain nerve inflammation disorders, and paraneoplastic syndromes that can occur alongside some cancers. Knowing whether this antibody is present helps explain unusual neurological symptoms and can guide what type of care or monitoring makes sense next.

What does a positive Amphiphysin antibody result mean?

A positive result means the antibody was detected in your blood, which suggests your immune system may be affecting your nervous system. This finding is often associated with conditions such as Stiff-Person syndrome, sensory neuropathy, or paraneoplastic neurological syndromes, sometimes linked to an underlying cancer. A positive result is a signal to pursue additional evaluation, especially if your symptoms are getting worse.

How often should I retest for this antibody?

If you're being monitored for a known condition or tracking how well a treatment is working, retesting every few months is common, but the right interval depends on your specific situation and symptom changes. If your first result was negative but symptoms persist or worsen, retesting sooner may make sense. Use the trends feature in your account to keep an eye on changes over time.

What should I do if my results are abnormal?

If your result is positive, take note of any symptoms you've been having and how they've changed recently, since this information is helpful for figuring out next steps. Because this antibody is linked to serious conditions, prompt follow-up testing or evaluation is important, and if you have severe symptoms like difficulty breathing, extreme stiffness, or sudden weakness, seek medical care right away. Keep your lab report handy since it clearly explains what your specific value means.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Amphiphysin Antibody Test - Nerve & Muscle Disorders

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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