What's this test for?

This test is ideal if you're following up on a tumor biopsy or diagnosis and need more information about how the tumor tissue is behaving. PTEN IHC (immunohistochemistry) looks at whether a tumor suppressor protein called PTEN is present or missing in tissue samples. It's often used alongside other pathology work to help understand a cancer diagnosis, without providing a written interpretation of the findings.

What's included in this test?

This test evaluates a single marker, the PTEN protein, using an immunohistochemistry (IHC) staining method on a tissue sample. It matters because PTEN normally acts as a brake on cell growth, and losing this protein is linked to certain cancers becoming more aggressive. Because no interpretation is included, the report shows the staining result only, without written clinical commentary.

What happens after I get my results?

Your results will be available in your account, showing whether PTEN protein expression was detected or lost in the tissue sample tested. Since this is a without-interpretation report, the raw finding is provided so it can be reviewed alongside your other pathology records and medical history. The standard lab report can be downloaded directly from your account at any time. If you're tracking multiple tests over time, you can view historical results using the trends feature in your account.

How can I naturally support healthy cell growth?

While no lifestyle change can restore a missing tumor suppressor protein, general habits that support healthy cells include eating a diet rich in vegetables and fiber, staying physically active, limiting alcohol, and avoiding tobacco. Getting enough sleep and managing stress can also help your body's natural repair processes work better. These habits are supportive measures and are not a substitute for appropriate medical follow-up on your test findings.

When will I get my results?

Results for this test are typically ready within about 7 days of your sample being processed at the lab. Tissue-based tests like this one can sometimes take a bit longer than standard blood work because of the specialized staining and review process involved. You'll see a notification in your account as soon as your report is ready to view.

Who should consider this test?

This test is generally considered by people who have already had a tumor biopsy and want additional information about the tumor's biological characteristics. It's commonly used in the context of certain cancers, such as prostate, endometrial, or breast cancer, where PTEN status can be relevant. It's a good next step when your existing pathology workup calls for additional tumor marker testing.

What does it mean if PTEN expression is lost?

Loss of PTEN expression means the tissue sample did not show the normal protein staining pattern, which can be associated with more aggressive tumor behavior in some cancers. This finding on its own doesn't tell the whole story — it's one piece of information among several used to understand a tumor. Discussing this result in the context of your full pathology report and treatment history is an important next step.

What causes loss of PTEN protein in tumor tissue?

PTEN loss usually happens because of a deletion or mutation in the PTEN gene within the tumor cells, which stops the cell from making the normal protein. This is a change that happens in the tumor tissue itself rather than something caused by diet or lifestyle. It's a well-studied genetic event seen across several cancer types.

How often should I retest?

This is typically a one-time test tied to a specific tissue sample rather than something retested on a regular schedule. If a new biopsy or tissue sample becomes available later, for example after treatment, retesting that new sample may provide updated information. Your retesting needs will depend on your individual situation and any new tissue samples that become available.

What should I do if my results show PTEN loss?

If your report shows loss of PTEN expression, it's a good idea to keep this result together with your other pathology and imaging records for a complete picture. Since this report doesn't include a written interpretation, understanding what it means for your specific situation typically involves looking at it alongside your full diagnostic history. If you have any concerning symptoms or your condition changes, seek medical care promptly.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

PTEN IHC Tumor Marker Test - Tissue Analysis

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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