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Proteinase-3 antibody test for detecting autoimmune vasculitis affecting kidneys and lungs

Proteinase-3 Antibody Test for Vasculitis Symptoms

Proteinase-3 Antibody

  • Detect early blood vessel inflammation
  • Screen for autoimmune kidney damage risks
  • Check unexplained lung and sinus symptoms
$253
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing unexplained symptoms like fatigue, joint pain, sinus problems, coughing up blood, or blood in your urine that could point to blood vessel inflammation. It helps check for a type of autoimmune activity where your immune system mistakenly attacks small blood vessels, which can affect organs like the kidneys and lungs. It's often used when there's concern about ongoing inflammation that doesn't have an obvious cause.

What happens after I get my results?

Your results will be available in your account, with each value's normal range clearly explained so you know exactly where you stand. If your result is elevated, next steps typically include seeking prompt medical care since this can signal active inflammation that needs attention quickly. You can download a standard lab report directly from your account at any time, and if you retest in the future, the trends feature lets you track changes over time.

Who should consider this test?

People with unexplained symptoms affecting their kidneys, lungs, sinuses, or joints that have lasted for weeks without a clear cause may want to consider this test. It's also useful for those who've had unusual lab findings, like blood or protein in urine, along with respiratory symptoms. Anyone concerned about ongoing, unexplained inflammation in the body may find this test provides helpful information.

What symptoms indicate I may need this test?
Common signs include persistent sinus issues, coughing up blood, shortness of breath, unexplained fatigue, joint or muscle pain, and skin rashes that don't go away. Blood or protein showing up in urine tests can also be a red flag. If you're noticing several of these symptoms together, especially if they're getting worse, this test can help investigate the cause.
When will I get my results?
Results are typically ready within about 7 days after your sample is collected at the lab. Once ready, you'll be able to view them securely in your account. You'll also be able to download a full lab report and track any future results over time using the trends feature.
How can I naturally support blood vessel health?
Eating an anti-inflammatory diet rich in fruits, vegetables, and omega-3 fatty acids (like fish and walnuts) can help support your body's natural inflammation response. Staying hydrated, avoiding smoking, and getting regular, moderate exercise also support healthy circulation and blood vessels. Managing stress through good sleep and relaxation techniques may help too, since chronic stress can worsen inflammation. These steps support general wellness but aren't a substitute for addressing an active autoimmune condition.
What is Proteinase-3 antibody and why does it matter?
Proteinase-3 antibody, often called PR3-ANCA, is a specific antibody your immune system may produce when it mistakenly targets your own blood vessels. It matters because when present at higher levels, it's closely linked to a type of vasculitis that can damage small blood vessels in the kidneys, lungs, and sinuses. Detecting it early can help identify inflammation before it causes lasting organ damage.
What does a high Proteinase-3 antibody result mean?
A high result suggests your immune system may be producing antibodies associated with vessel inflammation, which is seen in certain autoimmune vasculitis conditions. This doesn't automatically mean you have a disease, but it's a strong signal that further evaluation is important, especially if you have related symptoms. Because these conditions can progress quickly, an elevated result paired with symptoms should prompt fast follow-up care.
What causes an elevated Proteinase-3 antibody level?
Elevated levels are most often linked to ANCA-associated vasculitis, a group of conditions where the immune system attacks small blood vessels. Triggers can include certain infections, other autoimmune diseases, or in some cases, reactions to specific medications. In many cases, the exact trigger isn't fully understood, which is why testing and monitoring symptoms together is important.
How often should I retest?
If your first result comes back normal and you have no symptoms, retesting usually isn't needed unless new symptoms develop. If you've had a positive result or are managing symptoms, more frequent retesting, such as every few months, can help track how levels change over time. Using the trends feature in your account makes it easy to see patterns across multiple tests.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
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US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
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Demo results
Proteinase-3 (PR3) Antibody 1.2 AI (Antibody Index)
Demo results
Negative (<1.0) Positive (≥1.0)
1.2 AI (Antibody Index)

What this means

This result is within the negative range, meaning no significant PR3 antibody activity was detected. This suggests the immune-related blood vessel inflammation associated with certain vasculitis conditions is unlikely at this time. A negative result is reassuring, especially when paired with an absence of related symptoms.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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Proteinase-3 Antibody Test for Vasculitis Symptoms

  • Detect early blood vessel inflammation
  • Screen for autoimmune kidney damage risks
  • Check unexplained lung and sinus symptoms
$253
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.