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Prostate triple stain IHC test for men with prior biopsy findings suggestive of cancer

Prostate Triple Stain Biopsy Test (P504S, p63, Keratins)

Prostate Triple Stain (P504S, HMW Keratins, P63), IHC with Interpretation

  • Clarify unclear prostate biopsy results
  • Detect early prostate cancer signs
  • Distinguish precancerous changes from cancer
$834
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you've already had a prostate biopsy and the results were unclear or borderline. It's used when a small or ambiguous area of tissue makes it hard to tell whether cells are cancerous, precancerous, or simply benign. This test helps clarify a diagnosis that a standard biopsy review couldn't fully settle.

What's included in this test?

This test applies a combination of three antibody stains to a single tissue slide so specialists can compare cancerous and benign cell patterns side by side. Each stain targets a different feature: one highlights cells typical of prostate cancer, while the other two highlight the basal cell layer found in normal, non-cancerous prostate tissue. Looking at all three together makes it easier to tell benign changes apart from actual cancer, especially in a very small tissue sample.

What happens after I get my results?

Your results will be available in your account, along with an explanation of what the findings mean for the tissue sample analyzed. Since this is a diagnostic pathology test rather than a numeric biomarker test, the report will describe whether the stain pattern points toward benign tissue, precancerous changes, or cancer, and what that finding typically means next. You can download the full lab report from your account at any time, and if you have related follow-up testing in the future, you can track your test history through the trends feature. If your report indicates a finding that needs prompt attention, consider scheduling a follow-up procedure or additional testing right away.

How can I naturally support prostate health?
While this test result depends on cell patterns in a tissue sample rather than lifestyle factors, general prostate health can benefit from a diet rich in vegetables, tomatoes, and healthy fats, along with regular physical activity. Limiting red meat and high-fat dairy, staying at a healthy weight, and not smoking are also linked to better prostate outcomes. These habits won't change an existing tissue finding, but they support long-term prostate health going forward.
When will I get my results?
Results are typically ready within about 7 days, since this test involves detailed lab preparation and specialist review of the stained tissue slide. This is longer than a routine blood test because multiple stains need to be applied and carefully compared. You'll be notified as soon as your report is available in your account.
Who should consider this test?
This test is best for men who have already had a prostate biopsy with a small or borderline area of concern that couldn't be clearly classified as benign or cancerous. It's also useful when there's a need to distinguish cancer from a precancerous condition called prostatic intraepithelial neoplasia (PIN). If your prior biopsy report mentioned an inconclusive or atypical finding, this test can help provide a clearer answer.
What symptoms indicate I may need this test?
This test isn't ordered based on symptoms directly — it's used after a biopsy has already been done and the tissue findings are unclear. Symptoms that may have led to that original biopsy include urinary changes, elevated PSA blood levels, or an abnormal finding on a prior imaging or physical exam. If you're in this situation, this stain test is a logical next step for tissue that's already been collected.
What is prostatic intraepithelial neoplasia (PIN) and why does it matter?
PIN refers to prostate cells that look abnormal under a microscope but haven't yet become invasive cancer. It matters because some forms of PIN are linked to a higher chance of finding cancer nearby, so telling PIN apart from actual cancer changes how closely you might need to be monitored. This triple stain test helps make that distinction clearer, especially when the tissue sample is small.
How often should I retest?
Retesting isn't done on a routine schedule like a blood panel — it depends on what your original biopsy and this stain result show. If your results are inconclusive or borderline, another biopsy or repeat testing may be suggested to confirm the picture. If results clearly show benign tissue, your future testing schedule will typically follow standard prostate screening timelines like routine PSA checks.
What should I do if my results are abnormal?
If your report shows a finding suggestive of cancer or a high-risk precancerous change, don't wait — schedule a follow-up appointment or additional imaging and biopsy as soon as possible. Bring your full report, since it explains exactly which stain patterns were seen and where. Acting quickly on a concerning result gives you the most options for early treatment if needed.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Prostate Triple Stain (P504S / p63 / HMW Keratin) Pattern Positive for P504S, Negative for p63/HMW Keratin
Demo results
Benign Pattern Cancer-Associated Pattern
Positive for P504S, Negative for p63/HMW Keratin

What this means

This staining pattern shows cells lacking the basal cell layer (negative p63 and HMW keratin) while showing positive P504S staining, a pattern typically associated with prostate adenocarcinoma rather than benign tissue. This does not replace a full clinical picture, but it strongly supports the presence of cancerous cells in the sampled tissue area. A specialist review of the full slide alongside your original biopsy is the appropriate next step.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Prostate Triple Stain Biopsy Test (P504S, p63, Keratins)

  • Clarify unclear prostate biopsy results
  • Detect early prostate cancer signs
  • Distinguish precancerous changes from cancer
$834
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.