Why Private MD Labs?
90-day money-back guarantee Lab order in minutes Save a trip to the doctor Low prices since 2005 Labs within 2 miles
Diagnostic panel for adults with suspected liver autoimmune disease like PBC

Primary Biliary Cholangitis (PBC) Antibody Blood Test

Primary Biliary Cholangitis (PBC) Diagnostic Panel

  • Screen for autoimmune liver disease
  • Check unexplained itching and fatigue
  • Detect related autoimmune thyroid issues
$1626
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you're experiencing unexplained fatigue, itchy skin, dry eyes or mouth, or your recent bloodwork showed liver enzyme changes that suggest a possible liver condition. It helps evaluate whether an autoimmune liver disease called primary biliary cholangitis (PBC) could be causing your symptoms. It's also useful if you have a family history of autoimmune disease or have been told you may have an autoimmune liver or thyroid condition.

What's included in this test?

This panel checks several different antibodies that your immune system may produce when it mistakenly attacks liver or other tissues. Each antibody category gives different diagnostic information: some are highly specific markers for PBC itself, while others help identify related autoimmune conditions like Sjogren syndrome, autoimmune hepatitis, or autoimmune thyroid disease that often occur alongside it.

What happens after I get my results?

Your results will appear in your account with each antibody result explained alongside its normal reference range. If any antibody comes back positive, the report will note whether a reflex titer or pattern was run, and simple next steps like retesting or watching for new symptoms will be outlined. You can download a standard lab report from your account at any time, and the trends feature lets you track your antibody levels over time if you retest in the future. If any result suggests a serious or rapidly progressing condition, seek medical care promptly.

How can I naturally support liver health?
Eating a balanced diet low in processed foods and added sugar, limiting alcohol, and staying hydrated all support liver function. Regular moderate exercise and maintaining a healthy weight can reduce strain on the liver. Some people find that avoiding unnecessary medications or supplements that are hard on the liver, and getting enough sleep, also helps manage symptoms alongside any recommended lifestyle changes.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. Because this panel includes several antibody tests, some of which may trigger automatic reflex testing (like titers or patterns), turnaround can vary slightly depending on those additional steps. You'll receive a notification as soon as your results are posted to your account.
Who should consider this test?
This test is a good option for adults with unexplained itching, fatigue, or abnormal liver-related blood work, especially if a routine panel raised questions about liver health. It's also worth considering if you have a personal or family history of autoimmune conditions such as Sjogren syndrome, autoimmune hepatitis, or thyroid disease. People who've already had elevated liver enzymes on a basic metabolic or liver panel are common candidates.
What symptoms indicate I may need this test?
Common symptoms linked to PBC include persistent fatigue, itchy skin (especially at night), dry eyes or mouth, and mild discomfort in the upper right abdomen. Some people notice yellowing of the skin or eyes, dark urine, or pale stools in later stages. If you're experiencing several of these symptoms together, especially with abnormal liver blood work, this panel can help clarify what's going on.
What does a positive antibody result mean?
A positive result, such as for anti-mitochondrial antibody (AMA), means your immune system is producing antibodies commonly seen in people with PBC, though it doesn't confirm the disease on its own. Diagnosis typically requires looking at this result alongside liver-related blood work and, in some cases, additional evaluation. A positive result on other antibodies in this panel, like SSA/SSB or TPO, may point toward a related autoimmune condition instead of or in addition to PBC.
How often should I retest?
If your results are positive or borderline, retesting every 6 to 12 months can help track whether antibody levels or related liver markers are changing over time. If your results are negative but symptoms persist or worsen, retesting sooner or pairing this panel with additional liver function tests may be helpful. The trends feature in your account makes it easy to compare results across multiple tests.
What should I do if my results are abnormal?
Start by reviewing the explanation provided with your report to understand which antibodies were positive and what they typically indicate. Consider lifestyle steps that support liver health, such as reducing alcohol intake and eating a balanced diet, while monitoring your symptoms closely. If you notice worsening symptoms like jaundice, severe itching, or abdominal pain, seek medical care promptly, since these can signal disease progression that needs timely attention.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Anti-Mitochondrial Antibody (AMA) Positive (Titer 1:80)
Demo results
Negative Positive
Positive (Titer 1:80)

What this means

A positive AMA result means your immune system is producing antibodies that are commonly found in people with primary biliary cholangitis. This antibody is present in about 95% of people with PBC, but a positive result alone doesn't confirm the diagnosis without additional evaluation.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

Find a lab

Primary Biliary Cholangitis (PBC) Antibody Blood Test

  • Screen for autoimmune liver disease
  • Check unexplained itching and fatigue
  • Detect related autoimmune thyroid issues
$1626
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
Ask Me Anything

Your 24/7 Personal Lab Guide

Hi. Tell me what you want to check. I'll find the right blood test for you.

Just now
For informational purposes only. Not medical advice.