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HIV screening and RNA test for people on PrEP therapy monitoring

PrEP HIV Screening and RNA Test for Ongoing Prophylaxis

PrEP HIV-1/2 Antigen and Antibodies, Fourth Generation,Screen and HIV-1 RNA

  • Screen HIV status while on PrEP
  • Monitor prophylaxis safety and effectiveness
  • Detect early infection missed by standard tests
$655
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're currently taking PrEP (either the daily pill or the injectable shot) and need routine HIV monitoring while on prophylaxis. It's also useful if you've recently used PrEP and need to confirm your HIV status before continuing or restarting the medication. Because PrEP can sometimes mask early infection on standard tests, this combination approach gives a more complete picture.

What happens after I get my results?

Your results will show up in your account with a clear explanation of what each value means and whether it falls in the normal range. If everything comes back negative, you can continue your PrEP routine as planned and simply retest at your next scheduled interval. If either result raises a concern, the report will explain the next steps, and you should seek medical care right away for further evaluation. You can download a standard lab report anytime and use the trends feature to track your results over multiple testing cycles.

What is HIV pre-exposure prophylaxis (PrEP) and why does routine testing matter?

PrEP is medication that people at risk of HIV take to significantly lower their chances of getting infected, either as a daily pill or a periodic injection. Because no prevention method is 100% effective, routine testing while on PrEP catches any breakthrough infection early, when treatment works best. Regular testing also makes sure the medication is still the right choice for you and helps guide any adjustments to your prevention plan.

When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification as soon as your report is available in your account. Because this test combines two different lab methods, it can take a bit longer than a single quick test, so plan accordingly if you're on a specific PrEP dosing schedule.
Who should consider this test?
This test is a good fit for anyone who has taken oral PrEP in the last 3 months or received a cabotegravir injection in the past 12 months. It's also appropriate for people who want a thorough HIV status check before starting or continuing PrEP, since standard antibody tests alone might not catch a very recent infection in someone already on prophylaxis. If you fall into either of these groups, this combined screen gives a clearer answer.
What symptoms indicate I may need this test?
Most people on PrEP won't have obvious symptoms, which is exactly why routine testing matters. That said, flu-like symptoms such as fever, sore throat, swollen glands, or unusual fatigue within a few weeks of a potential exposure can sometimes signal an early infection and are a good reason to test sooner rather than waiting for your next scheduled check. If you experience any of these symptoms, seek medical care promptly in addition to getting tested.
How can I naturally support my immune system while on PrEP?
While no natural remedy replaces PrEP or HIV testing, keeping your immune system strong can help your body respond well overall. Eating a balanced diet, getting consistent sleep, managing stress, and avoiding excessive alcohol all support a healthy immune response. Staying on schedule with your PrEP doses and testing intervals remains the most important step for prevention.
What does a positive result mean?
A positive result on either part of this test means the lab detected signs of HIV, either through antibodies/antigens or through viral genetic material (RNA). This doesn't mean panic is necessary, but it does mean you should seek medical care right away to confirm the result and discuss treatment options, since early treatment leads to the best outcomes. Your PrEP regimen would also need to be reassessed based on this result.
How often should I retest while on PrEP?</br>
Testing frequency depends on your specific PrEP regimen; people on the daily pill typically test every 3 months, while those on the injectable version may follow a different schedule tied to their injection dates. Staying consistent with these intervals is one of the best ways to catch any issues early. Check your PrEP care plan or product confirmation for the specific interval that applies to you.
What should I do if my results are abnormal?
If your result is anything other than a clear negative, don't wait — seek medical care as soon as possible to get a confirmatory evaluation. Continue to avoid unprotected exposures in the meantime. Keep a copy of your lab report handy, as it will be useful for any follow-up testing or evaluation.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
HIV-1/2 Antigen/Antibody Screen Negative
Demo results
Negative Positive
Negative

What this means

A negative result means no HIV antigens or antibodies were detected in your sample, which is the expected result for someone whose PrEP is working as intended. This is a good sign, but continued routine testing is still important since it's your best tool for catching any rare breakthrough infection early.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

Find a lab

PrEP HIV Screening and RNA Test for Ongoing Prophylaxis

  • Screen HIV status while on PrEP
  • Monitor prophylaxis safety and effectiveness
  • Detect early infection missed by standard tests
$655
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.