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Fourth-generation HIV antigen/antibody test for sexually active adults on PrEP

PrEP HIV-1/2 Antigen and Antibody Blood Test

PrEP HIV-1/2 Antigen and Antibodies, Fourth Generation, with Reflexes

  • Detect early or acute HIV infection
  • Screen for HIV-1 and HIV-2
  • Check your status after exposure
$54
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're sexually active and want to know your HIV status, including early or acute infection. It's especially useful if you've had a potential exposure and want a fast, accurate answer using the same testing approach recommended by the CDC. Note that this specific test is not meant for people currently taking PrEP, since PrEP can affect results — those patients need an additional HIV-1 RNA test ordered alongside this one.

What happens after I get my results?

Your results will show up in your account with a clear explanation of what a positive, negative, or indeterminate result means. If your result comes back positive, the lab automatically runs a confirmatory antibody test and, if needed, an HIV-1 RNA test at no extra step on your part, so you get a clear final answer. You can download a standard lab report from your account any time, and if you test regularly, you can track your results over time using the trends feature. If you've had a recent exposure or symptoms are severe, don't wait on results — seek medical care right away.

Who should consider this test?

Anyone who is sexually active, has had a new or multiple partners, or wants a routine HIV screen should consider this test. It's also a good choice after a specific exposure event, since fourth-generation testing can catch acute infection earlier than older antibody-only tests. If you're currently using oral or injectable PrEP, this particular test isn't the right fit — you'll want the PrEP-specific combo test instead.

What symptoms indicate I may need this test?
Early HIV infection can cause flu-like symptoms such as fever, sore throat, swollen glands, rash, or fatigue that show up a few weeks after exposure. Many people, though, have no symptoms at all, which is why testing after a potential exposure matters even if you feel fine. If you've had unprotected sex, a shared needle exposure, or a partner who tested positive, this test is worth considering regardless of symptoms.
When will I get my results?
Results are typically ready in about 7 days. If your initial result is positive, the automatic reflex tests (confirmatory antibody test and, if needed, HIV-1 RNA) may add a little extra time since those are performed as follow-up steps. You'll be notified as soon as your final results are available in your account.
What is HIV antigen/antibody testing and why does it matter?
This fourth-generation test looks for both the p24 antigen (a piece of the virus itself) and antibodies your body makes in response to HIV. Testing for both means it can pick up infections earlier than antibody-only tests, sometimes within a few weeks of exposure. Catching HIV early matters because early treatment leads to much better long-term health outcomes and helps prevent transmission to others.
What does a positive result mean?
A positive antigen/antibody result means the test detected signs of HIV, but it's not the final word — the lab automatically runs a confirmatory test to verify infection and determine whether it's HIV-1 or HIV-2. If confirmed, starting treatment early is one of the most effective things you can do for your long-term health. Reach out to a local clinic or health department promptly to discuss next steps and treatment options.
What does a negative result mean?
A negative result usually means no HIV was detected, but timing matters — if you were tested very soon after a possible exposure, it's possible the virus hasn't built up enough to detect yet. If your exposure was within the last few weeks, consider retesting to confirm your status. If the initial result comes back negative or indeterminate but there's still concern about very early infection, the lab may automatically run an HIV-1 RNA test to check further.
How often should I retest?
If you're sexually active with new or multiple partners, testing every 3 to 6 months is a reasonable routine. After a specific exposure, testing right away and then again around 4-6 weeks later gives the most reliable picture, since it takes time for the body to produce detectable antigen or antibodies. People on PrEP should follow a different, more frequent testing schedule using the PrEP-specific combination test.
What should I do if my results are abnormal?
If your result is positive or indeterminate, don't panic — the lab automatically performs follow-up testing to clarify the result. In the meantime, avoid unprotected sex or sharing needles to prevent possible transmission while you wait for confirmation. Once you have a confirmed result, connecting with a local health clinic can help you understand treatment options and next steps quickly.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
HIV-1/2 Antigen/Antibody Negative
Demo results
Negative Positive
Negative

What this means

A negative result means no HIV antigen or antibodies were detected in your sample. If your last possible exposure was more than a few weeks ago, this is a reliable indicator that you do not have HIV. If your exposure was very recent, consider retesting in a few weeks to be sure.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

Find a lab

PrEP HIV-1/2 Antigen and Antibody Blood Test

  • Detect early or acute HIV infection
  • Screen for HIV-1 and HIV-2
  • Check your status after exposure
$54
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.