What's this test for?

This test is ideal if you're experiencing joint pain, skin thickening or tightening, unexplained muscle weakness, or symptoms of Raynaud's phenomenon like fingers turning white or blue in the cold. It helps check for signs of systemic sclerosis or overlapping connective tissue conditions that can cause these symptoms. It's often used when your symptoms overlap between skin, muscle, and joint issues and a clearer answer is needed.

What's included in this test?

This test looks for a specific autoantibody in your blood called PM/Scl-100. Autoantibodies are proteins your immune system makes that mistakenly target your own tissues, and finding this particular one can point toward systemic sclerosis or overlap conditions between scleroderma and myositis. Detecting it helps clarify a diagnosis when symptoms cross over between different connective tissue conditions.

What happens after I get my results?

Your results will show up in your account with the normal range explained so you know exactly what your value means. If your result is outside the normal range, the report will explain what that could indicate and whether retesting or additional evaluation makes sense; if a result looks dangerously abnormal, seek medical care promptly. You can download a standard lab report directly from your account at any time. You'll also be able to track this result over time using the trends feature if you test again in the future.

How can I naturally support connective tissue and immune health?

Eating an anti-inflammatory diet rich in fruits, vegetables, and omega-3 fatty acids (like fish or flaxseed) may help support your immune system and reduce inflammation. Gentle regular movement, like stretching or swimming, can help keep joints and skin more flexible. Managing stress through sleep, relaxation techniques, and avoiding smoking are also known to support overall immune balance. These steps don't replace medical treatment but can be helpful alongside it.

When will I get my results?

Results are typically available within about 7 days after your sample is processed at the lab. You'll get a notification once they're ready to view securely in your account. If it takes a bit longer, that can happen if additional confirmation testing is needed.

Who should consider this test?

This test is a good option for adults with unexplained skin tightening, joint pain, muscle weakness, or Raynaud's-type symptoms where fingers or toes change color in the cold. It's also useful if you have a family history of autoimmune or connective tissue disease and want to check for early markers. People already diagnosed with a related condition may also use it to clarify whether an overlap syndrome is present.

What symptoms indicate I may need this test?

Common symptoms include skin that feels tight, thick, or shiny, especially on the hands or face, along with joint pain and stiffness. Muscle weakness, fatigue, and difficulty swallowing can also be signs worth checking. Raynaud's phenomenon, where fingers or toes turn white or blue in cold temperatures, is another common symptom linked to this condition.

What does a positive PM/Scl-100 antibody result mean?

A positive result means your immune system has produced antibodies associated with systemic sclerosis or an overlap between scleroderma and myositis. This doesn't confirm a diagnosis on its own, but it's an important piece of the puzzle alongside your symptoms and other testing. If your result is positive, it's a good idea to seek a full evaluation to understand next steps.

What should I do if my results are abnormal?

If your result comes back positive, keep track of your symptoms like skin changes, joint pain, or muscle weakness so you have detailed information for further evaluation. Consider retesting or additional lab work to build a fuller picture over time. Seek medical care promptly if you experience severe symptoms like difficulty breathing or swallowing, or rapidly worsening skin or muscle changes.

How often should I retest?

If your first result is negative but symptoms persist or worsen, retesting every 6-12 months can help catch any changes early. If you've tested positive, tracking your levels periodically alongside symptom changes can help you and any care team monitor how things are progressing. Your healthcare situation and symptom pattern should guide the exact timing.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

PM/Scl-100 Antibody Test - Scleroderma Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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