What's this test for?

This test is ideal if you're experiencing frequent or slow-healing bone fractures, bone or joint pain, or if you've lost teeth early without an obvious cause. It's also useful if a family member has been diagnosed with hypophosphatasia, a rare condition that weakens bones and teeth, or if bloodwork already showed unusually low alkaline phosphatase. This urine test helps support a diagnosis and can also be used to monitor treatment if you're already being treated for this condition.

What's included in this test?

This test measures phosphoethanolamine (PEA) in a urine sample along with creatinine, which helps account for how concentrated or diluted your urine is at the time of collection. Measuring both together gives a more accurate, standardized picture of PEA excretion, since urine concentration can vary a lot throughout the day. This combination is what makes the result reliable enough to help support a diagnosis or monitor treatment over time.

What happens after I get my results?

Your results will be available in your account, with the normal range for phosphoethanolamine (PEA) and creatinine clearly explained next to your value. If your PEA level is elevated, the next step is usually further testing, such as checking alkaline phosphatase levels or genetic testing, to confirm what's causing the elevation. You can download a standard lab report from your account at any time, and if you're monitoring an existing condition or treatment, the trends feature lets you track your PEA levels over multiple tests to see how they change.

How can I naturally support healthy bones?

While elevated PEA itself isn't something you can fix with lifestyle changes, supporting your overall bone health is always a good idea. Getting enough calcium and vitamin D through food or sunlight, doing regular weight-bearing exercise like walking or light strength training, and avoiding smoking can all help maintain bone strength. These steps won't correct an underlying enzyme issue, but they support your skeleton while you sort out what's causing your symptoms.

When will I get my results?

Results for this test are typically ready within about 7 days of your sample being processed at the lab. You'll receive a notification once your results are posted to your account, where you can view your value alongside the reference range. If you need results faster for an urgent situation, reach out to the lab directly to ask about expedited options.

Who should consider this test?

This test is worth considering if you have unexplained bone fractures, especially ones that happen easily or heal slowly, bone or joint pain without a clear cause, or early loss of adult teeth with the roots still intact. It's also relevant if you have a family history of hypophosphatasia or if a routine blood test showed unusually low alkaline phosphatase activity. People already diagnosed with hypophosphatasia and undergoing enzyme replacement therapy can also use this test to monitor how well treatment is working.

What symptoms indicate I may need this test?

Watch for repeated or stress fractures, bones that heal slowly, ongoing bone or joint pain, and short stature or bowed limbs if these concerns started in childhood. Losing teeth early in life, especially with the tooth root still intact, is another key sign that's easy to overlook. If you or a family member show any of these patterns, this urine test can help clarify whether an underlying bone condition is involved.

What is phosphoethanolamine and why does it matter?

Phosphoethanolamine (PEA) is a small molecule that's normally broken down by an enzyme called alkaline phosphatase. When that enzyme doesn't work properly, as happens in hypophosphatasia, PEA builds up and spills into the urine at higher-than-normal levels. Measuring urine PEA gives a practical, non-invasive way to flag this enzyme problem, which is otherwise a rare and easy-to-miss cause of bone and dental issues.

What does a high PEA result mean?

A high PEA level in your urine suggests your body isn't breaking down this molecule normally, which is commonly seen in hypophosphatasia, a genetic condition affecting bone mineralization. It can also occasionally show up with other bone diseases, certain hormone disorders, or high blood pressure, so a high result on its own isn't a final diagnosis. Following up with additional testing, such as an alkaline phosphatase blood test or genetic testing, helps pin down the exact cause.

How often should I retest?

If you're being newly evaluated for symptoms, one test is usually enough to see if PEA is elevated and decide on next steps. If you've been diagnosed with hypophosphatasia and are on enzyme replacement therapy, retesting periodically, such as every few months or as advised by your treatment plan, can help track whether the therapy is working. Use the trends feature in your account to compare results over time and spot meaningful changes.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

PEA Urine Test - Hypophosphatasia Bone Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Phosphoethanolamine (PEA) Urine Test for Bone Health

Phosphoethanolamine (PEA), Urine with Creatinine

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

What's this test for?

What's included in this test?

What happens after I get my results?

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

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Phosphoethanolamine (PEA) Urine Test for Bone Health

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

1,000,000+ blood tests later, here's what our customers say