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PD-L1 IHC test for lung cancer patients considering immunotherapy eligibility

PD-L1 Lung Cancer Test for Immunotherapy Eligibility

PD-L1 Lung (Pembrolizumab or Cemiplimab), IHC

  • Check tumor PD-L1 protein levels
  • Assess immunotherapy treatment eligibility
  • Screen lung cancer treatment options
$2040
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you or someone in your care has been diagnosed with non-small cell lung carcinoma (NSCLC) and needs to find out if certain immunotherapy drugs could work. It looks at tumor tissue to see how much of a protein called PD-L1 is present, which helps determine eligibility for treatments like KEYTRUDA (pembrolizumab) or LIBTAYO (cemiplimab). This is typically ordered as part of a treatment planning process after a lung cancer diagnosis has already been made.

What happens after I get my results?

Your results will be available in your account along with an explanation of what the PD-L1 finding means for treatment eligibility. Because this is a qualitative tissue test tied to a specific cancer diagnosis, next steps usually involve discussing the report with your treatment team to decide if immunotherapy is a fitting option. A standard lab report is downloadable from your account at any time, and you can keep a record of this and any future related tests using the trends feature. If your report indicates a result that needs urgent clarification, reach out to your treatment center right away.

What symptoms indicate I may need this test?

This test isn't based on everyday symptoms — it's used after imaging and a biopsy have already confirmed non-small cell lung cancer. If you've been diagnosed with NSCLC and are exploring treatment options beyond surgery, chemotherapy, or radiation, this test helps figure out if immunotherapy is a realistic path. Symptoms like a persistent cough, chest pain, or unexplained weight loss are what typically lead to the original lung cancer workup, not to this specific test.

How can I naturally support lung health during cancer treatment?
While this test itself doesn't change with lifestyle habits, supporting your body during cancer treatment can still help you feel better day to day. Eating protein-rich foods, staying hydrated, and getting light physical activity when possible can help maintain strength during therapy. Avoiding smoking and secondhand smoke exposure is especially important for lung health. Always pair these habits with the guidance given by your treatment center.
When will I get my results?
Results for this test are typically ready within about 7 days after your tissue sample is processed at the lab. Because this involves specialized tissue staining and pathologist review, it takes a bit longer than a standard blood test. You'll be notified as soon as your report is available in your account.
Who should consider this test?
This test is meant for people who have already been diagnosed with non-small cell lung carcinoma and are exploring whether immunotherapy drugs like pembrolizumab or cemiplimab could be part of their treatment plan. It's typically ordered by a treatment team as part of building out a cancer care strategy, not as a general screening test. If you're newly diagnosed with NSCLC and want to understand all your treatment options, this is a relevant next step.
What is PD-L1 and why does it matter?
PD-L1 is a protein that some cancer cells use to hide from your immune system, essentially telling immune cells not to attack them. When a tumor has high levels of PD-L1, certain immunotherapy drugs can block this signal and help your immune system recognize and fight the cancer more effectively. Measuring PD-L1 levels in tumor tissue helps show whether this type of drug is likely to help in your specific case.
What does a high PD-L1 result mean?
A high PD-L1 result means a larger portion of your tumor cells are expressing this protein, which often suggests you may respond well to immunotherapy drugs like pembrolizumab or cemiplimab. This is generally seen as encouraging news for immunotherapy eligibility. Your full report will explain the specific scoring used and how it applies to your case.
What does a low PD-L1 result mean?
A low or negative PD-L1 result means fewer tumor cells are expressing this protein, which may mean immunotherapy alone is less likely to be effective for you. This doesn't rule out treatment entirely — it simply means other options, like chemotherapy, radiation, or combination therapies, may be considered instead. Your treatment team can help map out the best path based on this and other test findings.
What should I do if my results are abnormal?
If your PD-L1 result comes back differently than expected, don't panic — this is one piece of a larger picture used to plan lung cancer treatment. Bring the report to your treatment center so it can be reviewed alongside your imaging, biopsy, and other lab findings. Keeping a copy of your results and any related tests organized in your account can make these conversations easier and faster.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
PD-L1 Expression (Tumor Proportion Score) Positive (TPS 55%)
Demo results
Negative (TPS <1%) Positive (TPS ≥1%)
Positive (TPS 55%)

What this means

A positive result with a Tumor Proportion Score of 55% means more than half of the tumor cells tested show PD-L1 expression. This level of expression is generally associated with a higher likelihood of responding to immunotherapy drugs like pembrolizumab or cemiplimab. Your full report includes the exact scoring details used by the pathologist.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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PD-L1 Lung Cancer Test for Immunotherapy Eligibility

  • Check tumor PD-L1 protein levels
  • Assess immunotherapy treatment eligibility
  • Screen lung cancer treatment options
$2040
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.