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PD-1 IHC test for lymphoma diagnosis and cancer immunotherapy evaluation support

PD-1 Tissue Test — Lymphoma & Immunotherapy Marker

PD-1, IHC with Interpretation

  • Screen tissue for lymphoma markers
  • Assess tumor immune cell patterns
  • Support immunotherapy treatment planning decisions
$817
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you or someone in your care has a suspicious lymph node biopsy or tissue sample that needs further evaluation for T-cell lymphoma or Hodgkin lymphoma. It's also useful when there's a need to understand how tumor tissue interacts with the immune system before starting certain immunotherapy treatments. This test is typically ordered as a follow-up to imaging or biopsy findings, not as a first-line screening test.

What's included in this test?

This is a specialized immunohistochemistry (IHC) test that examines tissue samples for PD-1 protein expression, a marker found on certain immune cells. This single, focused test helps identify specific cell types and patterns that are important for diagnosing lymphomas and can also provide insight into how a tumor might respond to certain immune-based treatments.

What happens after I get my results?

Your results will be available in your account, with an explanation of what the finding means for the tissue sample tested. Since this is a specialized tissue-based test, next steps usually involve discussing the findings with the team managing your care plan, especially if further testing or treatment decisions depend on the result. You can download the full lab report directly from your account for your records. If you have follow-up testing over time, the trends feature lets you keep track of changes.

Who should consider this test?
This test is generally considered for people who already have a tissue biopsy that shows signs of possible lymphoma or another condition requiring immune cell marker analysis. It's also relevant for those exploring immunotherapy treatment options, since PD-1 expression can offer clues about how a tumor interacts with the immune system. This is a specialized, targeted test rather than a general wellness screening.
When will I get my results?
Results for this test are typically ready within about 7 days. This timeframe reflects the detailed lab processing required for tissue-based immunohistochemistry testing, which involves careful preparation and examination of the sample. You'll be notified as soon as your results are posted to your account.
What symptoms indicate I may need this test?
Symptoms that might lead to this type of testing include unexplained swollen lymph nodes, persistent fatigue, unexplained weight loss, or night sweats — all of which can be signs of lymphoma. However, this test is usually ordered after a biopsy has already been taken, not based on symptoms alone. If you're experiencing these symptoms, getting a tissue sample evaluated is the appropriate next step.
What is PD-1 and why does it matter?
PD-1 is a protein found on the surface of certain immune cells called T-cells, and it plays a role in regulating immune system activity. In cancer, PD-1 can be used by tumors to hide from the immune system, which is why measuring it in tissue samples helps identify certain lymphomas and predict how a tumor might respond to immune-based treatments. Understanding PD-1 levels in a sample gives useful information for diagnosis and treatment planning.
What does a high PD-1 expression result mean?
A high level of PD-1 expression in a tissue sample can indicate the presence of specific immune cell patterns associated with certain lymphomas, such as T-cell lymphomas or Hodgkin lymphoma. It may also suggest that a tumor could respond to treatments designed to block PD-1 activity. This finding is typically interpreted alongside other tissue markers for a complete picture.
How often should I retest?
Retesting frequency for this type of specialized tissue test depends entirely on your individual situation, such as whether you're monitoring treatment response or investigating a new biopsy. It's not a routine test that's repeated on a regular schedule like a wellness panel. Your testing schedule should be guided by the specific health situation prompting the original test.
What should I do if my results are abnormal?
If your results show abnormal PD-1 expression, the report will explain what the finding means for the tissue tested. Because this test relates to a serious diagnostic workup, it's important to follow up promptly with additional testing or the treatment planning process relevant to your situation. Keep a copy of your downloadable report handy for any future appointments or additional lab work.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
PD-1 (Programmed Death-1) Protein Expression Positive - Moderate Expression
Demo results
Negative Positive
Positive - Moderate Expression

What this means

A positive result means PD-1 protein was detected on immune cells within the tissue sample, which can be seen in certain lymphomas and in tumors that interact with the immune system. This finding is usually reviewed together with other tissue markers to reach a complete diagnosis. It does not by itself confirm a specific diagnosis but adds important information to the overall picture.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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PD-1 Tissue Test — Lymphoma & Immunotherapy Marker

  • Screen tissue for lymphoma markers
  • Assess tumor immune cell patterns
  • Support immunotherapy treatment planning decisions
$817
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.