What's this test for?

This test is ideal if you're experiencing unexplained neurological symptoms like muscle weakness, coordination problems, memory changes, seizures, or vision issues that haven't been explained by other testing. It looks for antineuronal antibodies, which are immune proteins that can attack the nervous system, sometimes as a reaction to a hidden tumor elsewhere in the body. This is often used when doctors suspect an autoimmune or paraneoplastic cause behind new or progressive neurological changes.

What happens after I get my results?

Your results will show up in your account with each antibody result explained, including what a positive or negative finding means and how it compares to the normal range. If any antibody comes back positive, the next step is usually confirmatory titer or line blot testing, which this panel already includes as a reflex step. Because these results can point toward serious underlying conditions, prompt follow-up action is important if results are abnormal. You can download the full lab report from your account any time, and use the trends feature to track results if you're retested in the future.

What's included in this test?

This panel uses indirect immunofluorescence across multiple neuronal and non-neuronal tissues, transfected substrate cells, radioimmunoassay, and confirmatory line blot testing to detect and identify antineuronal autoantibodies, with automatic reflex to titer testing when antibodies are found. Testing multiple antibodies and methods together increases the chance of catching a specific autoimmune pattern, which matters because different antibodies point to different underlying causes, including occult tumors, and different treatment paths.

How can I naturally support nervous system health?

While natural approaches can't reverse an autoimmune antibody reaction, supporting your nervous system overall can help you feel your best while you sort out results. Getting consistent sleep, eating an anti-inflammatory diet rich in omega-3s, staying physically active as tolerated, and managing stress can all support nervous system function. Avoiding alcohol and smoking also reduces added strain on your nervous system. These steps are supportive only and don't replace addressing the root cause found through testing.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed. This slightly longer timeframe reflects the specialized lab methods used, including immunofluorescence and confirmatory line blot testing when needed. You'll get a notification as soon as your results are available in your account.

Who should consider this test?

This test is a good fit for anyone with unexplained, progressive neurological symptoms such as sudden movement problems, cognitive decline, seizures, or vision changes, especially when a cause hasn't been found yet. It's also useful for people with a known cancer history who develop new neurological symptoms, since paraneoplastic antibodies can appear before a tumor is even found. People with a family history of autoimmune conditions may also want this as part of a broader workup.

What symptoms indicate I may need this test?

Common symptoms that prompt this testing include unsteady walking, muscle weakness, unusual eye movements, memory or personality changes, seizures, and trouble with speech or swallowing. These symptoms can develop gradually or appear suddenly and often don't fit a typical pattern seen with more common conditions. If these symptoms are severe or rapidly worsening, seek medical care right away rather than waiting for test results.

What does a positive antibody result mean?

A positive result means one or more antineuronal antibodies were detected, which suggests your immune system may be mistakenly attacking part of your nervous system. This can happen on its own or as a reaction to a tumor elsewhere in the body, which is why positive results often lead to additional imaging or cancer screening. The specific antibody identified helps narrow down the likely cause and appropriate next steps.

How often should I retest?

If your initial result is negative but symptoms continue or worsen, retesting after a few months can be helpful since some antibodies take time to reach detectable levels. If you've already tested positive and started addressing the underlying cause, periodic retesting can help track whether antibody levels are dropping in response to treatment. Your specific retesting schedule depends on your individual symptom pattern and history.

What should I do if my results are abnormal?

If you get a positive result, don't panic — this is a starting point for figuring out the cause, not a diagnosis on its own. Reasonable next steps include additional imaging studies to look for a hidden tumor, tracking your symptoms closely, and using the confirmatory titer results included in this panel to understand how strong the antibody signal is. If your symptoms are severe or getting worse quickly, seek medical care promptly.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Paraneoplastic Antibody Panel - Neurological Symptom Test

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Paraneoplastic Antibody Panel — Neurological Symptom Testing

Paraneoplastic Antibody Expanded Evaluation with Reflex to Titer and LB, CSF

Prescription & fees included

Easy to understand results

Fast & convenient