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Paraneoplastic antibody test for neurological symptoms linked to occult cancer risk

Paraneoplastic Antibody Test for Unexplained Neurological Symptoms

Paraneoplastic Antibody Evaluation w/Reflex to Titer and Line Blot,Basic

  • Detect antibodies linked to nerve symptoms
  • Screen for hidden tumor warning signs
  • Assess unexplained muscle weakness causes
$24727
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing unexplained neurological symptoms like muscle weakness, seizures, memory loss, coordination problems, or unusual sensory changes that haven't been explained by other causes. These symptoms can sometimes be linked to your immune system reacting to a hidden tumor somewhere in the body, a condition called a paraneoplastic syndrome. This test helps identify specific antibodies that may point to what's causing your symptoms.

What's included in this test?

This panel looks for a group of antibodies that your immune system may mistakenly produce when reacting to certain tumors, which can end up attacking nerve cells. Testing for several antibodies at once, with reflex to titer and line blot when needed, helps narrow down the exact pattern involved, which can guide what type of further workup makes sense. This layered approach increases the chance of catching a specific, identifiable cause behind confusing neurological symptoms.

What happens after I get my results?

Your results will show up in your account with each antibody result explained in plain language, including whether it falls in the normal or abnormal range. If any antibody comes back positive, further evaluation is a reasonable next step to look into the underlying cause, and if symptoms are severe or rapidly worsening, seeking medical care right away is important. You can download a standard lab report from your account at any time, and if you retest in the future, the trends feature lets you track any changes side by side.

How can I naturally support nervous system health?
While natural approaches can't replace addressing an underlying autoimmune trigger, general nerve-supportive habits include eating foods rich in B vitamins and omega-3 fatty acids, staying physically active to support circulation, getting consistent sleep, and managing stress through relaxation techniques. Avoiding alcohol and tobacco can also reduce added strain on the nervous system. These habits support overall nerve health but won't resolve an active autoimmune process on their own.
When will I get my results?
Results are typically ready within about 7 days after your sample is collected, since this test involves detailed antibody analysis including reflex testing when indicated. You'll get a notification once your results are posted to your account. Because reflex testing can add extra steps in the lab, some cases may take slightly longer than a standard panel.
Who should consider this test?
This test is worth considering if you have unexplained neurological symptoms such as sudden movement disorders, memory problems, seizures, or muscle weakness, especially if they came on relatively quickly. It's also relevant if you have a known cancer diagnosis and are experiencing new neurological symptoms that could be related. People with a family history of autoimmune conditions combined with unusual nerve symptoms may also find this test useful.
What symptoms indicate I may need this test?
Common symptoms include sudden or progressive difficulty with coordination, unexplained seizures, memory or personality changes, muscle weakness, vision changes, or unusual sensations like numbness and tingling that don't have an obvious explanation. Symptoms that appear alongside a cancer diagnosis or that develop quickly over weeks rather than years are also worth checking. If these symptoms are getting worse quickly, seeking medical care promptly is recommended.
What does a positive antibody result mean?
A positive result means your immune system has produced antibodies that specifically target nerve tissue, which can sometimes be a sign of an underlying tumor triggering the immune response. The specific antibody detected can help narrow down which type of syndrome or tumor might be involved. Because these results can be complex, prompt follow-up evaluation is recommended to understand the full picture and next steps.
How often should I retest?
If your first test comes back negative but symptoms continue or worsen, retesting after a few weeks to a couple of months can help catch antibodies that may not have been detectable initially. If you've had a positive result and are undergoing treatment, periodic retesting can help track whether antibody levels are changing over time. Your trends feature makes it easy to compare results from each testing round.
What should I do if my results are abnormal?
If you get a positive or abnormal result, the next step is usually further evaluation to look for an underlying cause, including imaging or additional testing since this can sometimes point to an occult tumor. In the meantime, keep a log of your symptoms and how they change, since this information is useful for any follow-up evaluation. If symptoms are severe, such as significant weakness, difficulty breathing, or seizures, seek medical care right away.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Antineuronal Nuclear Antibody (Anti-Hu, Anti-Yo, Anti-Ri Panel) Negative
Demo results
Negative Positive
Negative

What this means

A negative result means no paraneoplastic antineuronal antibodies were detected in your sample, which makes an autoimmune paraneoplastic cause less likely. A positive result would mean specific antibodies were found that attack nerve tissue, which can sometimes be linked to an underlying tumor.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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Paraneoplastic Antibody Test for Unexplained Neurological Symptoms

  • Detect antibodies linked to nerve symptoms
  • Screen for hidden tumor warning signs
  • Assess unexplained muscle weakness causes
$24727
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.