What's this test for?

This test is ideal if you're concerned about a personal or family history of breast, ovarian, pancreatic, or other cancers linked to PALB2 gene changes. It's also useful if you or a family member has a diagnosis of Fanconi Anemia or a suspected case, since this condition can be caused by changes in the same gene. Many people order this test after learning a close relative carries a PALB2 mutation or after a strong pattern of cancer appears in their family.

What happens after I get my results?

Your results will appear securely in your account, with a clear explanation of what a positive, negative, or uncertain finding means for the PALB2 gene. If a mutation is found, next steps typically include sharing the report with family members who may also want to get tested and considering more frequent cancer screening going forward. You can download the full lab report from your account at any time, and because this is a one-time genetic test, tracking over time isn't usually needed unless you're monitoring related family testing.

What's included in this test?

This test includes PALB2 gene sequencing and PALB2 deletion/duplication analysis. Sequencing reads through the gene's genetic code to spot small changes or typos, while deletion/duplication analysis checks for larger missing or extra pieces of the gene. Looking at the gene in both ways matters because some mutations are small changes in the DNA while others involve whole chunks being added or removed, and either type can raise cancer risk or point to Fanconi Anemia.

How can I naturally support my overall cancer risk profile?

While no lifestyle change can alter your genes, certain habits can help lower overall cancer risk regardless of your PALB2 status. Eating a diet rich in vegetables, fruits, and fiber, staying physically active, limiting alcohol, and avoiding tobacco are all linked to lower cancer risk. Regular self-exams and staying current on recommended cancer screenings are also practical steps you can take starting today.

When will I get my results?

Results are typically ready within about 7 days of your sample being received at the lab. Genetic tests like this one require detailed analysis, so turnaround can occasionally run slightly longer for complex cases. You'll be notified as soon as your results are posted to your secure account.

Who should consider this test?

This test is a good fit for people with a family history of breast, ovarian, pancreatic, or prostate cancer, especially if a relative has already tested positive for a PALB2 mutation. It's also relevant for anyone with a family history or personal features suggestive of Fanconi Anemia, such as unexplained bone marrow problems in childhood. People building a full picture of their family's cancer risk often start here.

What symptoms indicate I may need this test?

PALB2-related conditions don't usually cause symptoms on their own — instead, it's usually a pattern of family history that prompts testing, such as multiple relatives with breast or pancreatic cancer, or cancer diagnosed at a young age. For Fanconi Anemia, signs in a child might include unusual bruising, extreme tiredness from low blood counts, or unusual bone or growth differences. If any of these patterns exist in your family, this test can help clarify your risk.

What does a positive PALB2 result mean?

A positive result means a mutation was found in one or both of your PALB2 gene copies. One mutated copy raises your lifetime risk for certain cancers and means you carry a Fanconi Anemia gene change that could be passed to children. Two mutated copies (one from each parent) can cause Fanconi Anemia itself, so this finding often leads to closer monitoring and testing for other family members.

What causes a PALB2 mutation?

PALB2 mutations are inherited, meaning they're passed down from a parent through their DNA — they aren't caused by lifestyle, diet, or environmental exposures. Everyone inherits two copies of the PALB2 gene, one from each parent, and a mutation in even one copy can be passed on to the next generation. This is why testing often extends to siblings, parents, and children once a mutation is identified in one family member.

What should I do if my results are abnormal?

If a mutation is found, consider sharing your results with close biological relatives, since they may carry the same change and benefit from testing too. Increased or earlier cancer screening is a common next step, along with tracking any new symptoms closely. If you're planning a family, genetic counseling resources can help you understand what the result means for future children.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

PALB2 Gene Test - Hereditary Cancer & Fanconi Anemia

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

PALB2 Gene Test for Hereditary Cancer Risk

PALB2 Sequencing and Deletion/Duplication

Prescription & fees included

Easy to understand results

Fast & convenient

Prescription & fees included

Easy to understand results

Fast & convenient

What's this test for?

What's included in this test?

What happens after I get my results?

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PALB2 Gene Test for Hereditary Cancer Risk

Prescription & fees included

Easy to understand results

Fast & convenient

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