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NPM1 mutation MRD test for AML patients monitoring leukemia treatment response

NPM1 Mutation Test for AML Residual Disease Monitoring

NPM1 Mutation for MRD, Quantitative PCR

  • Monitor leukemia treatment response over time
  • Detect residual disease after AML therapy
  • Track relapse risk with sensitive testing
$2179
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're being treated for acute myeloid leukemia (AML) and have already been confirmed to carry an NPM1 gene mutation. It helps track whether tiny amounts of leukemia cells are still present in your body after treatment, a status known as minimal residual disease (MRD). This information is used to gauge how well treatment is working and whether additional therapy may be needed.

What happens after I get my results?

Your results will appear in your account with an explanation of what your NPM1 mutation level means and how it compares to prior results. If your level is detectable, the report will outline what that may mean for your treatment plan and next steps, and if it's very high or rising quickly, you should seek medical care promptly. You can download a standard lab report anytime from your account, and because MRD monitoring relies on tracking change over time, our trends feature lets you compare each new result against your testing history.

What symptoms indicate I may need this test?

This test isn't for diagnosing new symptoms — it's a follow-up tool for people already diagnosed with NPM1-mutated AML. Signs that ongoing monitoring is worthwhile include recent induction chemotherapy, a history of AML relapse, or your care plan calling for regular residual disease checks. If you're experiencing new fatigue, unusual bruising, frequent infections, or fevers during or after AML treatment, those are reasons to seek medical care right away rather than wait for a routine MRD check.

How can I naturally support healthy blood cell recovery?
While no lifestyle change can treat leukemia or replace medical therapy, supporting your body during and after treatment can help you feel your best. Eating protein-rich, well-balanced meals, staying hydrated, and getting adequate rest help support bone marrow recovery and immune function. Avoiding infections through good hand hygiene and food safety is especially important when blood counts are low, and light activity, if approved, can help maintain energy and strength.
When will I get my results?
Results for this quantitative PCR test are typically available within about 7 days of your sample being processed at the lab. Because this is a specialized molecular test, it takes a bit longer than routine bloodwork, so you'll see a pending status in your account until the analysis is complete. You'll get a notification as soon as your results are ready to view.
Who should consider this test?
This test is best suited for people previously diagnosed with NPM1-mutated AML who have completed or are undergoing treatment. It's commonly used after induction therapy to check how effective treatment has been, and periodically afterward to catch any early signs of relapse. It is not a general cancer screening test and is not appropriate for people without a known NPM1 mutation diagnosis.
What is NPM1 mutation and why does it matter?
NPM1 is a gene that normally makes a protein involved in cell growth control. In about 30% of AML cases, this gene picks up a small mutation that changes the protein's structure, and this mutated version can be used like a fingerprint to track leukemia cells in the body. Because the mutation is specific to the cancer cells, doctors can use highly sensitive tests like this one to detect even tiny amounts of remaining disease that standard tests might miss.
What does a detectable NPM1 result mean?
A detectable or rising NPM1 mutation level suggests that some leukemia cells are still present in the body, even if you feel well and other test results look normal. Depending on the level and trend, this can signal a higher chance of relapse and may prompt closer monitoring or a change in treatment approach. If your result shows a significant increase, seek medical care promptly to discuss what it means for your specific situation.
How often should I retest for NPM1 MRD status?
Retesting schedules for MRD monitoring are typically set based on your specific treatment timeline, often every few months after initial therapy and more frequently if a prior result was borderline or rising. Consistent, regularly spaced testing is what makes the trends feature most useful, since small changes over time carry more meaning than a single result. If you're unsure of timing, the general guidance is to retest on the schedule outlined at the time of your original diagnosis and treatment plan.
What should I do if my results are abnormal?
If your NPM1 level comes back detectable or has increased from a prior test, don't panic, but don't ignore it either — seek medical care promptly to discuss the result in the context of your full treatment history. In the meantime, focus on maintaining good nutrition, avoiding illness exposure, and keeping up with any scheduled follow-up testing. Keeping a record of your results over time using the trends feature can help identify patterns early.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
NPM1 Mutation (Quantitative PCR, MRD) Detectable, 0.08% NPM1/ABL1 ratio
Demo results
Undetectable (Negative) Detectable (Positive)
Detectable, 0.08% NPM1/ABL1 ratio

What this means

A detectable result means a small number of leukemia cells carrying the NPM1 mutation are still present. This is used alongside your treatment history to assess your current disease status and relapse risk.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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NPM1 Mutation Test for AML Residual Disease Monitoring

  • Monitor leukemia treatment response over time
  • Detect residual disease after AML therapy
  • Track relapse risk with sensitive testing
$2179
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.