What's this test for?

This test is ideal if you're being treated for acute myeloid leukemia (AML) or have a normal karyotype AML diagnosis and need more information about your specific disease type. It looks for a genetic change called an NPM exon 12 mutation, which helps show how your leukemia may respond to treatment. It's also used to help track whether small amounts of disease remain after treatment.

What's included in this test?

This test looks specifically for mutations in exon 12 of the NPM1 gene using a cell-based analysis method. This particular genetic marker matters because it's found only in AML cells, never in healthy cells, making it a reliable way to confirm diagnosis and track treatment progress in normal-karyotype AML.

What happens after I get my results?

Your results will show up in your account along with an explanation of what a positive or negative finding means. If a mutation is found, next steps usually involve working with your treatment plan to track disease response and considering repeat testing at intervals to monitor minimal residual disease. You can download a standard lab report anytime from your account, and the trends feature lets you track results if you retest over time. If your result indicates something urgent or unexpected, seek medical care right away.

How can I naturally support my immune system during treatment?

While no natural remedy treats AML or changes genetic mutations, supporting your body during treatment can help you feel better overall. Eating a balanced diet with adequate protein, staying well hydrated, getting rest, and avoiding raw or undercooked foods (which carry infection risk when immunity is low) are commonly recommended. Gentle movement like short walks can help maintain energy levels between treatments. Always confirm any supplement use is safe with your treatment team since some can interact with chemotherapy.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed. You'll get a notification as soon as your report is available in your account, so you don't need to check back repeatedly.

Who should consider this test?

This test is generally considered for people already diagnosed with AML who have a normal karyotype on standard cytogenetic testing, since NPM1 mutations are especially relevant in this group. It may also be useful for monitoring purposes during and after treatment. It is not a general screening test for people without an AML diagnosis or suspicion.

What symptoms indicate I may need this test?

AML symptoms can include ongoing fatigue, unexplained bruising or bleeding, frequent infections, fever, bone or joint pain, and unexplained weight loss. These symptoms alone don't confirm AML, but if you've already had blood work suggesting leukemia, this test helps characterize the specific type further. Seek medical care promptly for severe or worsening symptoms like uncontrolled bleeding or high fever.

What is the NPM1 gene and why does it matter?

NPM1 is a gene that normally helps cells function properly, but mutations in exon 12 of this gene are found in a significant portion of AML cases with a normal karyotype. This mutation matters because it's linked to a better response to standard chemotherapy compared to some other AML subtypes. It also gives doctors a specific marker to track over time to see if leukemia cells are still present after treatment.

How often should I retest?

Retesting frequency depends on your individual treatment plan, but this type of test is often repeated at key points such as after completing initial treatment and at intervals afterward to monitor for minimal residual disease. Your treatment plan will typically define the exact schedule based on your specific situation. Tracking results over time in your account can help you and your treatment team see patterns.

What should I do if my results are abnormal?

If the NPM1 mutation is detected, this doesn't necessarily mean treatment isn't working — it's one piece of a larger picture used alongside other tests. Review the detailed report in your account, track any changes over time using the trends feature, and factor this information into ongoing treatment decisions. If you experience worsening symptoms alongside an abnormal result, seek medical care promptly.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

NPM1 Mutation Test - AML Diagnosis & Monitoring

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

NPM1 Gene Mutation Test for AML Monitoring

NPM (Exon 12) Mutation Analysis, Cell-based

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

What's this test for?

What's included in this test?

What happens after I get my results?

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NPM1 Gene Mutation Test for AML Monitoring

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

1,000,000+ blood tests later, here's what our customers say