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Nicotine and cotinine blood test for tobacco use and exposure detection

Nicotine and Cotinine Blood Test for Tobacco Exposure

Nicotine and Cotinine, Serum/Plasma

  • Detect recent tobacco or nicotine use
  • Confirm smoke-free progress after quitting
  • Screen for secondhand smoke exposure
$394
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're trying to confirm tobacco or nicotine exposure, whether for personal health tracking, a cessation program, or an employer or insurance requirement. It's also useful if you want to check how much secondhand smoke exposure might be affecting you. Many people use it to verify they've stayed smoke-free after quitting.

What happens after I get my results?

Your results show up in your account with the normal ranges explained so you know exactly what your nicotine and cotinine levels mean. If levels are higher than expected, next steps might include cutting back on tobacco products or nicotine replacement therapy and retesting in a few weeks to track your progress. You can download a standard lab report anytime from your account, and the trends feature lets you compare results over time if you're working on quitting.

What symptoms indicate I may need this test?

You might consider this test if you're experiencing cravings, irritability, or trouble sleeping that could be tied to nicotine use or withdrawal. It's also worth checking if you've been around heavy secondhand smoke and want to know your exposure level. Some people test simply to confirm compliance with a smoke-free commitment.

How can I naturally reduce nicotine exposure?
Avoiding smoking areas, vaping, and secondhand smoke are the most direct ways to lower your levels. Staying hydrated and eating a balanced diet can help your body clear nicotine and its byproducts faster. Regular exercise and stress-management techniques like deep breathing can also reduce cravings that lead to tobacco use.
When will I get my results?
Results are typically ready within about 7 days of your sample being tested. Once ready, they'll be posted directly to your account, and you'll get a notification so you can log in and review them right away.
Who should consider this test?
This test is a good fit for anyone trying to quit smoking or vaping and wanting proof of progress, people exposed to heavy secondhand smoke, and those who need documentation of tobacco-free status for work, insurance, or personal reasons. It's also useful for people monitoring a household member's smoking cessation efforts.
What is cotinine and why does it matter?
Cotinine is a byproduct your body makes when it processes nicotine, and it sticks around in your blood much longer than nicotine itself—up to several days. Because of this longer window, cotinine is the more reliable marker for figuring out how much tobacco exposure you've had recently, even if you haven't smoked in the last day or two.
What does a high cotinine result mean?
A high cotinine level usually means recent and possibly regular exposure to nicotine, whether from direct smoking, vaping, or heavy secondhand smoke. If your result is higher than you expected, consider reducing time around smokers, switching to nicotine-free alternatives, or reaching out to a cessation program. Retesting after a few weeks of reduced exposure can help you see if your efforts are working.
What causes unexpectedly high nicotine or cotinine levels?
The most common cause is direct tobacco or vape use, but heavy, prolonged secondhand smoke exposure can also raise levels noticeably. Some nicotine replacement products, like patches or gum, will also show up on this test, so factor that in if you're using them to quit.
How often should I retest?
If you're actively trying to quit, retesting every 4-6 weeks can help you track your progress and stay motivated. If you're testing for compliance or exposure verification, follow the specific timeline required by whoever requested proof of your status. Otherwise, testing once to establish a baseline and again after major lifestyle changes is usually enough.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Cotinine 12 ng/mL
Demo results
Non-user (<10 ng/mL) Tobacco user (≥10 ng/mL)
12 ng/mL

What this means

A cotinine level of 12 ng/mL suggests recent nicotine exposure, either from direct tobacco or vape use or heavy secondhand smoke. This is above the typical non-user threshold, meaning some level of nicotine exposure occurred in the past few days.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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Nicotine and Cotinine Blood Test for Tobacco Exposure

  • Detect recent tobacco or nicotine use
  • Confirm smoke-free progress after quitting
  • Screen for secondhand smoke exposure
$394
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.