What's this test for?

This test is ideal if you're being evaluated for a blood disorder that causes your body to make too many blood cells, or if you've already been diagnosed with a myeloproliferative neoplasm and need more information about it. It looks for specific gene changes that help explain why the condition developed and whether certain targeted treatments could work for you. It's also useful for tracking your condition over time after diagnosis or during treatment.

What's included in this test?

This panel checks three genes known to drive myeloproliferative neoplasms. Each gene works through a shared internal signaling pathway that tells blood cells to grow and divide, so finding a mutation in any one of them helps explain the root cause of the disorder and points toward treatments that specifically target that pathway.

What happens after I get my results?

Your results will show up in your account with a plain-language explanation of what each gene finding means. If a mutation is found, the next step is usually discussing targeted treatment options and setting up a follow-up testing schedule to track how your condition responds over time. You can download a standard lab report directly from your account at any time. Because this is a molecular marker test, the trends feature lets you compare results across multiple testing dates to see how your levels of disease activity change.

What is a myeloproliferative neoplasm and why does it matter?

A myeloproliferative neoplasm, or MPN, is a condition where your bone marrow makes too many blood cells because of a genetic glitch that keeps growth signals switched on. It matters because untreated MPNs can raise your risk of blood clots, an enlarged spleen, and in some cases progression to more serious bone marrow disease. Identifying the exact gene involved helps guide which treatments, including JAK2 inhibitor medications, are most likely to help.

When will I get my results?

Results are typically ready within about 7 days of your sample being tested. Genetic panels like this one require more detailed lab analysis than a standard blood test, which is why the turnaround is a bit longer. You'll get a notification as soon as your results are posted to your account.

Who should consider this test?

This test is a good fit for anyone with unexplained high red blood cell, platelet, or white blood cell counts on a routine blood count, or anyone with symptoms like unusual clotting, itching after a warm shower, or an enlarged spleen. It's also recommended for people already diagnosed with an MPN who want a clear molecular marker to track their disease. People with a family history of blood disorders may also want this information.

What symptoms indicate I may need this test?

Common signs include unexplained fatigue, itching that gets worse after a hot shower or bath, night sweats, unusual bruising or blood clots, and a feeling of fullness or pain on the left side of your abdomen from an enlarged spleen. Some people notice frequent headaches, dizziness, or reddish skin. If a routine blood test already shows unusually high red cell, platelet, or white cell counts, that's another strong reason to get this panel.

What does a positive JAK2, CALR, or MPL mutation result mean?

A positive result means one of these three growth-signal genes has a mutation that's driving your bone marrow to overproduce blood cells. This doesn't mean the outcome is the same for everyone — which gene is involved, and the specific mutation type, changes the outlook and treatment approach. It also means you may be a candidate for JAK2 inhibitor medications that specifically target this overactive pathway.

How often should I retest?

If you've already started treatment, retesting every few months can help track whether your mutation levels are dropping in response to therapy. If you're newly diagnosed and not yet on treatment, your retesting schedule will depend on how your blood counts and symptoms are trending. Regular monitoring makes it easier to catch changes early and adjust your approach.

What should I do if my results are abnormal?

If a mutation is found, focus on staying well hydrated, avoiding tobacco, and managing cardiovascular risk factors like blood pressure and cholesterol, since MPNs raise clotting risk. Keep track of new symptoms like severe headaches, vision changes, or leg swelling, and seek immediate medical care if these occur since they can signal a clot. Continue regular monitoring through retesting so you and your care plan can adjust as needed.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

MPN Mini Panel - JAK2, CALR & MPL Gene Test

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]