What's this test for?

This test is ideal if you're concerned about a personal or family history of multiple colon polyps or colorectal cancer at a young age. It looks for changes in the MUTYH gene that cause MUTYH-associated polyposis (MAP), a condition that significantly raises the lifetime risk of colon and small bowel cancer. It's especially useful if a close relative has been diagnosed with MAP or if colon cancer runs in your family.

What happens after I get my results?

Your results will be available in your secure account, with an explanation of what a positive or negative finding means for the MUTYH gene. If a pathogenic variant is found, next steps typically include more frequent colon screening and discussing testing with blood relatives who may share the same risk. Your full lab report can be downloaded directly from your account, and if you test again in the future, you can track your genetic testing history through the trends feature.

What symptoms indicate I may need this test?

You may want this test if you've had many colon polyps found during a colonoscopy, especially 10 or more over your lifetime. It's also worth considering if you've had colorectal cancer diagnosed before age 50, or if a sibling or parent has had MAP or a high polyp count. A strong family pattern of colon cancer across generations is another common reason people seek this test.

How can I naturally support colon health?

While genetics can't be changed through lifestyle, you can support your colon health with a diet high in fiber, fruits, and vegetables, and lower in red or processed meats. Staying active, maintaining a healthy weight, limiting alcohol, and not smoking are all linked to lower colon cancer risk. These habits are especially useful alongside regular colonoscopy screening if you carry a MUTYH variant.

When will I get my results?

Results are typically ready within about 7 days of your sample being received at the lab. Genetic tests like this one require careful analysis, so processing takes a bit longer than routine blood work. You'll receive a notification as soon as your results are posted to your account.

Who should consider this test?

This test is a good fit for people with a personal history of multiple colon polyps, early-onset colorectal cancer, or a family history of MAP. It's also useful for siblings or children of someone already diagnosed with a MUTYH mutation, since MAP is a recessive condition requiring two altered gene copies. People building a family history profile for cancer risk planning may also benefit.

What is MUTYH-associated polyposis and why does it matter?

MUTYH-associated polyposis (MAP) is an inherited condition caused by changes in both copies of the MUTYH gene, which normally helps repair damaged DNA. When this repair function doesn't work properly, colon cells are more likely to develop into polyps and eventually cancer. It matters because people with MAP have up to an 80% lifetime risk of colorectal cancer, but early detection through genetic testing allows for closer monitoring and earlier intervention.

What does a positive MUTYH result mean?

A positive result means a pathogenic variant was found in one or both copies of your MUTYH gene. Having two altered copies (one from each parent) confirms a MAP diagnosis and means a much higher lifetime risk of colon polyps and cancer. Having just one altered copy makes you a carrier, which may still slightly raise colorectal cancer risk and is important information for family planning and relatives' testing.

How often should I retest?

Genetic testing for a specific gene like MUTYH generally only needs to be done once, since your DNA sequence doesn't change over time. However, if you initially tested negative but new family history emerges, or if testing technology improves significantly, retesting or expanded panel testing could be worth considering. Regular colon cancer screening, on the other hand, is an ongoing process separate from this one-time genetic test.

What should I do if my results are abnormal?

If a MUTYH variant is found, the most important next step is starting more frequent colonoscopy screening, often beginning earlier and repeating more often than average-risk guidelines suggest. Sharing your result with blood relatives is also valuable, since siblings and children may want to get tested themselves. Keeping a downloaded copy of your report handy for future screening appointments can help ensure your care team has the full picture.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

MUTYH Gene Test - Colon Polyposis Cancer Risk

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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