What's this test for?

This test is ideal if you're experiencing joint pain, muscle weakness, swollen fingers, skin rashes, or unexplained fatigue that could point to an autoimmune condition. These symptoms often overlap between several connective tissue diseases, making it hard to know what's going on without lab work. This panel helps identify whether an autoimmune process affecting your connective tissue could be responsible for what you're feeling.

What's included in this test?

This panel checks for two main markers: a general autoimmune screening antibody and a more specific antibody linked to mixed connective tissue disease. The general screen helps catch a wide range of autoimmune activity, while the more specific marker helps narrow down whether mixed connective tissue disease in particular is a likely explanation. Testing both together gives a more reliable picture than checking just one on its own.

What happens after I get my results?

Your results will show up in your online account, with each value's normal range explained in plain language so you know what a positive or negative result means. If your ANA screen comes back positive, the lab automatically runs additional titer and pattern testing on the same sample, so you get a fuller picture without needing a second draw. The report is downloadable at any time, and if your results are unclear or symptoms continue, retesting or additional targeted panels can be a helpful next step. You can also track any future results over time using the trends feature in your account.

How can I naturally support my immune system function?

While you can't cure an autoimmune condition through lifestyle alone, some habits may help calm overall inflammation and support your body's balance. Eating a diet rich in vegetables, omega-3 fats, and whole foods while limiting processed sugar can help reduce inflammatory triggers. Getting consistent sleep, managing stress through activities like walking or meditation, and staying active with low-impact exercise can also make a noticeable difference. Avoiding smoking and excess alcohol is another simple step that supports immune balance.

When will I get my results?

Results for this panel are typically ready within about 7 days of your sample being collected. If your initial screen is positive, the automatic reflex testing for titer and pattern is included in that same timeframe, so you won't need to wait for a separate round of testing. You'll get a notification as soon as your results are posted to your account.

Who should consider this test?

This test is a good option if you have ongoing joint pain, muscle weakness, puffy or swollen fingers, Raynaud's-like color changes in your hands, or unexplained skin changes that haven't been explained by anything else. It's also useful if you have a family history of autoimmune or connective tissue diseases and want a baseline check. People already being monitored for a possible autoimmune condition may also use this panel to track changes over time.

What symptoms indicate I may need this test?

Common symptoms include joint pain and stiffness, muscle weakness, swelling in the hands or fingers, fatigue that doesn't improve with rest, skin rashes, and fingers that turn white or blue in the cold. Some people also notice mouth sores, hair loss, or low-grade fevers with no clear cause. If several of these symptoms show up together and stick around, it's worth checking your autoimmune markers.

What does a high ANA titer mean?

A high ANA titer, especially above 1:1000, means your immune system is producing antibodies that target your own cell nuclei, which is a strong signal seen in most people with mixed connective tissue disease. On its own, a high titer doesn't confirm a specific diagnosis, since it can appear in several autoimmune conditions or even in some healthy people. It's most meaningful when combined with the RNP antibody result and your symptom pattern.

What causes a positive RNP antibody result?

A positive RNP antibody result usually means your immune system is mistakenly targeting a specific protein-RNA complex inside your cells, which is closely tied to mixed connective tissue disease. It can occasionally show up in other autoimmune conditions like lupus as well. The exact reason some people's immune systems start doing this isn't fully understood, but genetics and environmental triggers are both thought to play a role.

What should I do if my results are abnormal?

If your ANA or RNP results come back positive, start by reviewing the detailed explanation in your report to understand your specific titer and pattern. Keep a symptom log noting joint pain, skin changes, fatigue, or other issues so you can track how things progress. Consider retesting in a few months to see if levels are changing, and seek prompt medical care if you develop severe symptoms like significant swelling, breathing trouble, or intense muscle weakness.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

MCTD Panel - ANA and RNP Antibody Blood Test

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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