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Nutrition-focused test checking B12 and folate deficiency via MMA and homocysteine

Vitamin B12 Deficiency Blood Test (MMA & Homocysteine)

Methylmalonic Acid and Homocysteine

  • Check vitamin B12 deficiency signs
  • Screen for heart disease risk
  • Monitor fatigue and nerve symptoms
$126
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing fatigue, tingling in your hands or feet, memory problems, or unexplained weakness that could point to a vitamin B12 or folate deficiency. It's also useful if a recent blood test showed larger-than-normal red blood cells (macrocytosis), since that can be a sign of a deficiency. This test helps confirm whether low B12 or folate is behind your symptoms and checks a marker linked to heart health.

What happens after I get my results?

Your results will show up in your account with each value's normal range clearly explained, so you can see right away if your Methylmalonic Acid and Homocysteine levels fall outside the typical range. If either marker is elevated, simple next steps like increasing B12 or folate intake through food or supplements, and retesting in a few months, are usually appropriate; if levels are very high, seek medical care promptly. You can download a standard lab report from your account at any time, and use the trends feature to track how your levels change over time.

What symptoms indicate I may need this test?

Common signs include ongoing tiredness, numbness or tingling in your hands and feet, trouble concentrating, mood changes, or pale skin. Some people also notice a sore tongue, mild balance issues, or a family history of B12/folate deficiency, especially if they follow a vegan or vegetarian diet. If a routine blood count showed unusually large red blood cells, that's another reason to check these markers.

How can I naturally support healthy B12 and folate levels?
Eating more B12-rich foods like eggs, dairy, fish, and meat can help if your diet has been low in these, while leafy greens, beans, and fortified grains boost folate intake. If you follow a vegan or vegetarian diet, a B12 supplement is often recommended since plant foods rarely contain enough. Cutting back on excess alcohol and managing digestive issues (which can affect absorption) also supports healthy levels over time.
When will I get my results?
Results are typically ready within about 7 days of your lab visit. You'll get a notification once they're posted to your account, where you can view a clear breakdown of your Methylmalonic Acid and Homocysteine levels alongside their reference ranges.
Who should consider this test?
This test is a good fit for people with symptoms of B12 or folate deficiency, those with a diet low in animal products, older adults (who absorb B12 less efficiently), and anyone whose routine bloodwork flagged larger-than-normal red blood cells. It's also worth considering if you have a family or personal history of cardiovascular issues, since elevated homocysteine is linked to heart disease risk.
What is Homocysteine and why does it matter?
Homocysteine is a substance your body makes when it breaks down protein, and normally B12 and folate help clear it from your blood. When levels build up, it's been linked to a higher risk of heart and blood vessel problems. Keeping it in a healthy range is one piece of protecting your long-term cardiovascular health.
What does high Methylmalonic Acid mean?
A high MMA level usually points to a vitamin B12 deficiency, since your body can't properly process certain compounds without enough B12. This might explain symptoms like fatigue, nerve tingling, or brain fog. Increasing B12 intake through diet or supplements and retesting after a few months can help confirm the levels are improving.
What causes high Homocysteine or MMA levels?
The most common causes are low intake of vitamin B12 or folate, often from a plant-based diet, poor absorption due to digestive conditions, or age-related changes in how the body absorbs nutrients. Certain medications and excessive alcohol use can also interfere with B12 absorption. In some cases, genetic factors affecting nutrient metabolism play a role.
How often should I retest?
If you're starting supplementation or making dietary changes to address a deficiency, retesting in about 8-12 weeks is a reasonable timeframe to see if levels are improving. Once your levels are stable and in a healthy range, checking once a year, or as symptoms arise, is generally enough. Use the trends feature in your account to keep an eye on changes over time.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Homocysteine 18.2 umol/L
Demo results
Low Optimal (5-15 umol/L) High
18.2 umol/L

What this means

A homocysteine level of 18.2 umol/L is above the optimal range, which is often linked to low vitamin B12 or folate. Elevated homocysteine has also been associated with increased cardiovascular risk over time.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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Vitamin B12 Deficiency Blood Test (MMA & Homocysteine)

  • Check vitamin B12 deficiency signs
  • Screen for heart disease risk
  • Monitor fatigue and nerve symptoms
$126
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.