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Urine metanephrines test for evaluating pheochromocytoma and adrenal tumor symptoms

Metanephrines Urine Test for Adrenal Tumor Symptoms

Metanephrines, Fractionated, LC/MS/MS, Random Urine

  • Screen for adrenal tumor causes
  • Check unexplained blood pressure spikes
  • Assess stress hormone imbalances
$602
First results as soon as overnight*

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Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you're experiencing episodes of high blood pressure, pounding headaches, sudden sweating, or a racing heart that come and go without a clear cause. These symptoms can sometimes point to a rare adrenal gland tumor called pheochromocytoma, which releases stress hormones into your body in bursts. This urine test helps check whether your body is producing unusually high levels of these hormones.

What's included in this test?

This test measures fractionated metanephrines in a random urine sample, which are breakdown products of stress hormones made by your adrenal glands. Checking these levels matters because a spike can be a sign of an adrenal tumor that's overproducing hormones like adrenaline and noradrenaline, which can drive dangerous blood pressure swings if left unaddressed.

What happens after I get my results?

Your results will be available in your account, with each value's normal range explained so you can see exactly where you fall. If your levels are elevated, next steps typically involve seeking follow-up testing to confirm the finding, since results can be affected by stress, certain foods, or medications. The standard lab report is downloadable directly from your account, and you can track your results over time using the trends feature if you retest in the future.

How can I naturally support healthy adrenal hormone balance?
While natural remedies can't fix an adrenal tumor if one is present, you can support your body's stress response by managing daily stress through deep breathing, regular sleep, and limiting caffeine and nicotine, which can trigger hormone surges. Regular gentle exercise like walking can also help keep blood pressure steadier. If your symptoms include severe or sudden episodes of high blood pressure, that warrants prompt medical attention rather than a wait-and-see approach.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. You'll receive a notification once your report is available in your account, where you can view and download it.
Who should consider this test?
This test is a good fit for people who have unexplained episodes of high blood pressure that spike and then return to normal, especially when paired with headaches, sweating, and heart palpitations. It's also useful for people with a family history of adrenal tumors or certain genetic conditions that raise the risk of pheochromocytoma. If standard blood pressure treatments haven't controlled your symptoms, this test can help identify a hormonal cause.
What symptoms indicate I may need this test?
Common symptoms include sudden episodes of high blood pressure, pounding or rapid heartbeat, severe headaches, heavy sweating, and feelings of anxiety or panic that come on suddenly. These episodes often last minutes to hours and can be triggered by stress, exercise, or certain foods. If you notice a pattern of these symptoms happening in bursts, it may be worth checking your metanephrine levels.
What does high metanephrine mean?
A high result means your body may be producing too much of certain stress hormones, which can happen with an adrenal gland tumor like pheochromocytoma. It can also occur due to certain medications, intense physical stress, or even some foods eaten before the test. Because of these factors, an elevated result is usually followed by repeat testing to confirm before further steps are taken.
What causes high metanephrine levels?
The most common cause of a true elevation is a tumor on the adrenal gland that produces excess stress hormones, but levels can also be temporarily raised by intense exercise, high stress, certain medications, or foods like coffee and chocolate close to testing. This is why the test is sometimes repeated under controlled conditions to rule out these everyday influences. Reviewing what you ate, drank, and any medications taken before your sample helps make sense of an unexpected result.
How often should I retest?
If your first result comes back elevated, retesting is usually recommended fairly soon under controlled conditions to confirm the finding. If your results are normal but your symptoms continue, retesting during or shortly after an episode may give more useful information. Otherwise, this isn't a routine test that needs regular repeating unless your symptoms change or persist.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

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Demo results
Normetanephrine (Urine) 485 mcg/24hr
Demo results
Normal (<443 mcg/24hr) Elevated (≥443 mcg/24hr)
485 mcg/24hr

What this means

This result is above the typical normal range, which can indicate your body is producing excess stress hormones. Elevated levels are sometimes linked to an adrenal gland tumor, but can also be caused by stress, certain foods, or medications taken before the test.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
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Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Metanephrines Urine Test for Adrenal Tumor Symptoms

  • Screen for adrenal tumor causes
  • Check unexplained blood pressure spikes
  • Assess stress hormone imbalances
$602
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.