What's this test for?

This test is ideal if you or a family member has been diagnosed with colorectal, endometrial, or certain skin (sebaceous) tumors and there's concern the cancer may be hereditary. It's often used when a pathologist or genetic counselor suspects Lynch syndrome (also called HNPCC), a condition that raises the risk of developing certain cancers at a younger age or having multiple family members affected. This panel looks directly at tumor tissue to see if it shows a pattern linked to this inherited condition.

What's included in this test?

This panel checks four mismatch repair proteins in tumor tissue to see whether one or more of them is missing, which is the hallmark finding in most Lynch syndrome cases. Looking at all four together gives a more complete picture than checking just one, since different families can have defects in different proteins. This helps clarify whether a cancer diagnosis might be linked to an inherited condition rather than occurring by chance.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a normal versus abnormal pattern looks like for each of the four proteins tested. If results are abnormal, the report includes guidance on the recommended next step in the workup, such as additional confirmatory genetic testing. Because this is a tissue-based analysis rather than a routine blood marker, retesting isn't typically needed, but you can keep a copy of your standard lab report downloadable from your account for future reference. Any related family screening test results can also be tracked over time using the trends feature.

Who should consider this test?

This test is best suited for people who have already been diagnosed with colorectal cancer, endometrial cancer, or certain sebaceous skin tumors, especially if diagnosed at a younger age or with a family history of similar cancers. It's also useful for families being evaluated for Lynch syndrome after a relative's diagnosis. If you're unsure whether your situation fits, review the pre-collection instructions on your order confirmation or check with the lab about tissue sample requirements before ordering.

When will I get my results?

Results are typically ready within about 7 days after your tumor tissue sample is processed at the lab. Because this test involves detailed tissue staining and review, it takes a bit longer than a standard blood test. You'll be notified as soon as your report is available in your account.

What symptoms indicate I may need this test?

There usually aren't symptoms that point directly to needing this test — it's typically ordered after a colorectal, endometrial, or sebaceous tumor has already been diagnosed. Signs that suggest a hereditary pattern worth investigating include being diagnosed with one of these cancers before age 50, having multiple family members with colon, endometrial, or related cancers, or having more than one of these cancers yourself over time. If this sounds like your situation, this tumor panel can help clarify whether an inherited cause is likely.

What is Lynch syndrome and why does it matter?

Lynch syndrome is an inherited condition that reduces the body's ability to repair small errors in DNA, which raises the risk of developing colorectal, endometrial, and several other cancers, often at a younger age than usual. It matters because identifying it can change how often someone gets screened for cancer and can alert other family members to consider their own risk. Catching this pattern early allows for more frequent monitoring, which can lead to finding future cancers sooner when they're easier to treat.

What does an abnormal result on this panel mean?

An abnormal result means one or more of the four proteins tested is missing from the tumor tissue, which suggests the cancer may be related to Lynch syndrome rather than happening sporadically. This finding doesn't confirm the diagnosis on its own — it's a signal that further genetic testing is recommended to look for the specific inherited change. Your report will outline the suggested next step based on which protein pattern was found.

What should I do if my results are abnormal?

If your results come back abnormal, the next recommended step is usually confirmatory genetic testing to identify the specific gene change involved, and your report will spell out that recommendation. It's also a good idea to share this information with close biological relatives, since they may want to consider their own cancer risk and screening schedule. In the meantime, staying current with recommended cancer screenings (like colonoscopies) is a practical step you can take right away.

How often should I retest?

This is a one-time tissue analysis tied to a specific tumor sample, so it generally isn't repeated the way blood tests are. If a new tumor develops later, testing that new tissue separately may be recommended. Any follow-up genetic testing recommended after an abnormal result is typically a separate, one-time test rather than something done on a regular schedule.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Lynch Syndrome Tumor Panel - Hereditary Cancer Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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