What's this test for?

This test is ideal if you or a family member has been diagnosed with colorectal, endometrial, or certain skin (sebaceous) tumors and there's concern the cancer may be linked to an inherited condition called Lynch syndrome. It's also useful if you have a strong family history of these cancers, especially at a young age, and want to understand whether an inherited mismatch repair problem could be involved. This panel examines the tumor tissue itself rather than blood, looking for clues that point toward a hereditary cause.

What's included in this test?

This panel checks four mismatch repair proteins in tumor tissue using a lab technique called immunohistochemistry (IHC). Looking at all four together matters because loss of even one protein can signal an underlying DNA repair defect, and the specific pattern of loss helps narrow down which gene may be affected. This information is a key first step in figuring out whether a cancer diagnosis might be linked to an inherited syndrome.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a normal versus abnormal pattern looks like for each of the four proteins tested. If a result is abnormal, the report includes guidance on recommended next steps in the workup, such as additional genetic testing to confirm a hereditary link. You can download the full standard lab report from your account at any time, and if you undergo related testing in the future, you can track those results together over time using the trends feature.

How can I naturally support healthy DNA repair and cancer prevention?

While no lifestyle change can undo an inherited genetic difference, some habits support your body's overall ability to repair cells and lower cancer risk. Eating a diet rich in vegetables, fruits, and fiber, limiting processed and red meat, staying physically active, and avoiding tobacco and excess alcohol are all linked to lower colorectal cancer risk. Regular cancer screening on a schedule appropriate for your personal and family history is one of the most protective steps you can take.

When will I get my results?

Results for this tumor tissue panel are typically ready within about 7 days after the sample is processed at the lab. Because this test involves detailed tissue staining and interpretation, it takes a bit longer than a standard blood test. You'll be notified as soon as your results are posted to your account.

Who should consider this test?

This test is a good option for people already diagnosed with colorectal, endometrial, sebaceous, or other related tumors where a hereditary cause is suspected. It's also worth considering if you have close relatives who were diagnosed with these cancers at a young age or if multiple family members have had similar cancers. Anyone building a clearer picture of their family cancer risk pattern may find this panel helpful as a starting point.

What symptoms or family history might mean I need this test?

You might consider this test if you or a relative were diagnosed with colorectal or endometrial cancer before age 50, or if several family members across generations have had colon, uterine, ovarian, or related cancers. A personal or family history of multiple different cancers, or unusual skin growths called sebaceous tumors, can also be a signal. These patterns don't confirm a hereditary condition, but they're reasons to look closer with tumor testing like this one.

What is Lynch syndrome and why does it matter?

Lynch syndrome is an inherited condition where certain genes that normally fix small errors in DNA don't work properly, allowing mistakes to build up and increasing the risk of colorectal, endometrial, and several other cancers over a lifetime. It matters because people with Lynch syndrome often benefit from starting cancer screening earlier and more frequently than average. Identifying it can also alert family members to consider their own testing.

What does an abnormal (loss of protein expression) result mean?

An abnormal result means one or more of the four proteins tested weren't detected in the tumor tissue, which suggests the DNA mismatch repair system isn't working normally in that tumor. This doesn't automatically mean you have Lynch syndrome, but it's a strong signal worth following up on with the additional workup steps outlined in your report. Many people take this as a cue to pursue confirmatory genetic testing and discuss more frequent cancer screening going forward.

What should I do if my results are abnormal?

Start by carefully reading the recommended next steps included in your report, which typically point toward confirmatory genetic testing. It's also a good idea to share this information with close blood relatives, since an inherited finding can affect their cancer risk too. In the meantime, staying current on recommended cancer screenings is one of the most practical steps you can take while you sort out next steps.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Lynch Syndrome Tumor Panel - Hereditary Cancer Testing

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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