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Lymphocyte clonality PCR test for diagnosing lymphoma and blood cell cancers

Lymphocyte Clonality PCR Test — Lymphoma Diagnostic Panel

Lymphocyte Clonality Panel, PCR

  • Detect abnormal lymphocyte growth patterns
  • Screen for lymphoma and leukemia signs
  • Clarify unexplained swollen lymph nodes
$7006
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
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Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're being evaluated for an unexplained swollen lymph node, unusual blood cell counts, or a suspected lymphoid cancer. It helps determine whether a group of white blood cells is growing as a normal immune response or as an abnormal, single-origin (clonal) population that can indicate lymphoma or leukemia. It's typically used alongside other testing to help sort out unclear or borderline findings.

What's included in this test?

This panel looks at several key genes involved in immune cell development, which lets it detect whether B-cells or T-cells are multiplying from a single abnormal cell (clonal) versus a normal, diverse immune reaction. Testing multiple gene regions at once increases the chance of catching abnormal patterns that a single-gene test might miss, especially in tricky or early-stage cases.

What happens after I get my results?

Your results will be posted securely in your account, with an explanation of what the finding means in plain language. Because this is a specialized test, next steps usually involve reviewing the result together with your other recent lab work and imaging, and retesting is generally only needed if new symptoms develop or your care team recommends monitoring. You can download a standard lab report from your account at any time, and if you have follow-up testing later on, you'll be able to track results over time using the trends feature. If your result suggests something urgent, such as rapidly worsening symptoms, seek medical care right away.

How can I naturally support healthy immune cell function?
While this test looks for a specific genetic pattern that lifestyle changes can't reverse, supporting your general immune health is still worthwhile. Eating a balanced diet rich in fruits, vegetables, and lean protein, getting consistent sleep, managing stress, and avoiding smoking all help your immune system function well. These habits won't change a clonality result, but they support your overall well-being during any diagnostic process.
When will I get my results?
Results for this test are typically ready within about 7 days of your sample being processed at the lab. This turnaround reflects the detailed genetic analysis involved in checking multiple gene regions. You'll receive a notification as soon as your results are available in your account.
Who should consider this test?
This test is generally considered when someone has an unexplained enlarged lymph node, abnormal results on a blood cell count, or a biopsy finding that needs further clarification. It's also useful for people whose earlier lymphoid tissue findings were inconclusive and need a more definitive answer about whether cells are clonal or reactive. Discuss your specific situation and symptoms before ordering to make sure this is the right test.
What symptoms indicate I may need this test?
Common reasons people pursue this test include a lymph node that stays swollen for weeks without an obvious cause, unexplained fevers, night sweats, unintended weight loss, or persistent fatigue. Abnormal findings on a prior blood test or biopsy showing an unusual population of lymphocytes is another common trigger. If you're experiencing several of these symptoms together, this test can help clarify what's happening at the cellular level.
What is lymphocyte clonality and why does it matter?
Lymphocyte clonality refers to whether a group of immune cells (lymphocytes) all descended from one single original cell, versus being a mixed, diverse population as you'd expect from a normal immune response. A 'clonal' pattern can be a sign of a lymphoid cancer such as lymphoma or leukemia, while a 'polyclonal' pattern usually points to a normal reactive process, like fighting an infection. This distinction is a key piece of information used to help sort out ambiguous lymph node or blood findings.
What does a positive (clonal) result mean?
A clonal result means the lab found evidence that a group of B-cells or T-cells share the same genetic rearrangement, suggesting they all came from a single original cell. This pattern raises concern for a lymphoid malignancy and typically prompts additional testing, such as imaging or a tissue biopsy, to get a full picture. It does not automatically confirm cancer, but it's an important piece of information for your overall diagnostic workup.
What should I do if my results are abnormal?
If your result shows a clonal pattern, don't panic, but do treat it as a signal to follow up with additional testing rather than something to watch and wait on. Gather your full test history, including any biopsy or imaging reports, since these results are most meaningful when interpreted together. If you're experiencing worsening symptoms like persistent fevers, drenching night sweats, or rapid weight loss, seek medical care promptly.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

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Demo results
Lymphocyte Clonality (IGK/IGH/TCRB/TCRG Gene Rearrangement) Polyclonal
Demo results
Polyclonal (Normal) Clonal (Abnormal)
Polyclonal

What this means

A polyclonal result means the lymphocytes tested show a diverse, mixed genetic pattern, which is what's expected from a normal immune response. This is a reassuring finding and does not suggest a lymphoid cancer. A clonal result, by contrast, would suggest the cells came from a single abnormal origin and would need further follow-up.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
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Lymphocyte Clonality PCR Test — Lymphoma Diagnostic Panel

  • Detect abnormal lymphocyte growth patterns
  • Screen for lymphoma and leukemia signs
  • Clarify unexplained swollen lymph nodes
$7006
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.