What's this test for?

This test is ideal if you're already diagnosed with non-small-cell lung cancer (NSCLC) and need more information about your specific tumor type. It looks for a change in the ROS1 gene that occurs in a small percentage of NSCLC cases, which can affect which treatments are likely to work best for you. This is especially useful if you're exploring targeted therapy options instead of, or alongside, standard chemotherapy.

What's included in this test?

This test uses a specialized lab technique called FISH (fluorescence in situ hybridization) to look directly at the tumor tissue for a rearrangement in the ROS1 gene. This matters because tumors with this specific genetic change tend to respond differently to certain medications than tumors without it, so identifying it helps guide more personalized treatment planning.

What happens after I get my results?

Your results will appear securely in your account, with an explanation of what a positive or negative ROS1 rearrangement result means. If your result is positive, a common next step is discussing targeted therapy options such as tyrosine kinase inhibitors with your treatment team, since research shows these can be effective for ROS1-positive tumors. You can download the full lab report from your account at any time, and if you undergo repeat testing later in your treatment journey, you'll be able to track changes over time using the trends feature.

How can I naturally support lung and immune health during cancer treatment?

While no natural remedy replaces targeted cancer treatment, some everyday habits can support your body during this time. Eating a balanced diet rich in fruits, vegetables, and lean protein helps maintain strength and energy. Gentle physical activity, adequate sleep, staying hydrated, and avoiding smoking or secondhand smoke can also help support your overall well-being alongside your treatment plan.

When will I get my results?

Results for this test are typically available within about 7 days after your sample is processed at the lab. This timeframe reflects the specialized nature of FISH testing, which requires careful lab analysis of tumor tissue. You'll receive a notification as soon as your results are ready to view in your account.

Who should consider this test?

This test is best suited for people who have already been diagnosed with non-small-cell lung cancer and are working through treatment decisions. It's particularly relevant if standard treatments haven't been effective or if you and your treatment team are considering targeted therapy options. Your treatment team may also request this test as part of a broader tumor profiling workup.

What does a positive ROS1 rearrangement result mean?

A positive result means the specific genetic change in the ROS1 gene was found in your tumor sample, which occurs in roughly 1.7% of NSCLC cases. This is actually useful information because tumors with this change have shown positive responses to certain targeted medications, like crizotinib, in clinical research. This result opens up a specific treatment pathway that may not have been considered otherwise.

What does a negative ROS1 result mean?

A negative result means this particular gene rearrangement was not detected in your tumor sample. This doesn't rule out cancer or other treatable genetic changes — it simply means this specific pathway isn't likely to be the right treatment target for you. Other biomarker tests may still be useful to explore additional treatment options.

How often should I retest?

This is typically a one-time test done at diagnosis or when treatment decisions are being reconsidered, rather than something retested on a regular schedule. However, if your tumor changes or stops responding to treatment over time, retesting tumor tissue may provide updated information. Your care plan will guide whether and when repeat testing makes sense.

What should I do if my results are abnormal?

If your result comes back positive for the ROS1 rearrangement, the most important next step is discussing targeted therapy options with your treatment team as soon as possible. Bring your downloadable lab report to that conversation so all your treatment options can be reviewed together. Acting quickly on this information can help open up effective, more personalized treatment paths sooner.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

ROS1 Lung Cancer Test - Targeted Therapy Guidance

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]