What's this test for?

This test is ideal if you're experiencing muscle weakness, drooping eyelids, double vision, or trouble swallowing that comes and goes or worsens with activity. These symptoms can point to myasthenia gravis, an autoimmune condition where your body's own antibodies interfere with nerve-to-muscle signaling. This test looks for one specific antibody, anti-LRP4, that shows up in some people with this condition who test negative on the more common antibody tests.

What happens after I get my results?

Your results will show up in your account along with an explanation of what a positive or negative result means. If your result is positive, a reasonable next step is discussing the finding with a specialist who can evaluate your symptoms further and consider additional testing. If it's negative but you still have symptoms, retesting or exploring other antibody tests (like anti-AChR or anti-MuSK) may make sense. You can download the full lab report from your account anytime, and if you retest later, you'll be able to track changes over time using the trends feature.

Who should consider this test?

This test is a good fit for people with unexplained muscle weakness, especially weakness that affects the eyes, face, throat, or limbs and fluctuates throughout the day. It's especially useful if you've already tested negative for the two more common myasthenia gravis antibodies (anti-AChR and anti-MuSK) but your symptoms still suggest the condition. People with a family history of autoimmune disease may also want to consider it if they're having similar symptoms.

What symptoms indicate I may need this test?

Common signs include drooping eyelids, blurred or double vision, slurred speech, difficulty chewing or swallowing, and arm or leg weakness that gets worse with activity and better with rest. Some people notice these symptoms flare up later in the day or after physical exertion. If you're having any combination of these symptoms, especially if they come and go, this test can help identify an autoimmune cause.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification once they're available in your account, where you can view the full report and what your result means.

What is myasthenia gravis and why does it matter?

Myasthenia gravis is an autoimmune condition where your immune system mistakenly attacks the connection point between your nerves and muscles, called the neuromuscular junction. This disrupts normal signaling and leads to muscle weakness that can affect your eyes, face, throat, and limbs. Catching it early matters because untreated cases can sometimes affect breathing muscles, and simple lifestyle adjustments and treatments can significantly improve day-to-day function.

How can I naturally support muscle and nerve health?

While you can't treat an autoimmune antibody issue with lifestyle changes alone, supporting your overall energy and muscle function can help you feel better day to day. Getting enough rest, pacing physical activity to avoid overexertion, and eating a balanced diet rich in vitamins B12 and D can support nerve and muscle health. Managing stress is also helpful since stress can sometimes worsen autoimmune symptoms. These steps work alongside, not instead of, appropriate evaluation of a positive result.

What does a positive LRP4 antibody result mean?

A positive result means your body is producing antibodies that target the LRP4 protein, which plays a role in keeping your muscles properly connected to your nerves. This finding, especially alongside symptoms like muscle weakness, supports a possible diagnosis of myasthenia gravis. It's a good idea to follow up with further evaluation, since antibody levels alone don't determine how severe symptoms might become.

How often should I retest?

If your first result is negative but symptoms persist, retesting after a few months or when symptoms change can be helpful, since antibody levels can shift over time. If you're positive and being evaluated for treatment, retesting frequency is often tied to how your symptoms are tracked rather than a fixed schedule. Your results page notes when it might make sense to check again based on your specific case.

What should I do if my results are abnormal?

If you get a positive result, the next step is usually a more detailed clinical evaluation to confirm the diagnosis and figure out the best way to manage symptoms. In the meantime, avoid overexertion, get plenty of rest, and pay attention to any new or worsening symptoms like trouble breathing or swallowing, which need urgent attention. Keep a symptom log so you can track patterns and share them during follow-up care.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

LRP4 Antibody Test - Myasthenia Gravis Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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