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JC virus DNA test for immunocompromised patients monitoring PML risk

JC Virus DNA Urine Test for Immunocompromised Monitoring

JC Polyoma Virus DNA, Quantitative, Real-Time PCR, Urine

  • Detect active JC virus reactivation
  • Monitor brain infection risk levels
  • Track immune system virus activity
$1763
First results as soon as overnight*

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Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you're immunocompromised, especially if you have HIV or are on certain immune-suppressing medications, and need to check for JC virus activity. JC virus can cause a serious brain condition called PML (progressive multifocal leukoencephalopathy), so catching an active infection early matters. It's also useful if you've had neurological symptoms like vision changes, weakness, or confusion and your situation calls for ruling out this virus.

How should I prepare for this test?

How can I naturally support my immune system while managing JC virus risk? While there's no natural remedy that clears JC virus itself, keeping your immune system as strong as possible is your best defense against it becoming active. Eating a balanced diet, getting consistent sleep, managing stress, and staying on top of any prescribed immune-related treatments all help your body keep the virus in check. Avoiding unnecessary immune-suppressing substances, like excess alcohol, can also support your overall resilience.

What happens after I get my results?

Your results will show up in your account as a viral load number along with an explanation of what that range means. If JC virus DNA is detected, especially at higher levels, the report will explain what that suggests and note when urgent follow-up is needed. You can download a standard lab report from your account at any time, and if you retest later, the trends feature lets you track whether your viral load is rising, falling, or staying stable.

When will I get my results?
Results for this test are typically ready within about 7 days of your sample being received at the lab. Because this is a specialized PCR test, it takes a bit longer than routine bloodwork to process accurately. You'll get a notification as soon as your results are posted to your account.
Who should consider this test?
This test is a good fit for people who are immunocompromised, such as those living with HIV/AIDS, organ transplant recipients, or people taking certain immune-modulating medications. It's also relevant for anyone who has developed new neurological symptoms while on these types of treatments. If you fall into one of these groups, checking JC virus activity can help catch problems early.
What symptoms indicate I may need this test?
Symptoms like sudden vision problems, muscle weakness on one side of the body, difficulty speaking, memory problems, or personality changes can be signs of PML, especially in people who are immunocompromised. These symptoms shouldn't be ignored since PML can progress quickly. If you're experiencing any of these along with a weakened immune system, this test can help determine if JC virus is involved.
What is JC virus and why does it matter?
JC virus is a very common virus that most people pick up harmlessly earlier in life and that stays dormant without ever causing problems. In people with weakened immune systems, though, it can reactivate and attack the brain, causing PML, a serious and sometimes life-threatening condition. This test measures how much of the virus's genetic material is in your urine, which helps show whether the virus is active.
What does a high JC virus level mean?
A high or detectable JC virus DNA level means the virus is actively replicating, which is a bigger concern if your immune system is already weakened. This doesn't automatically mean you have PML, but it's a signal that closer monitoring or follow-up care may be needed. If your result is high, especially alongside any neurological symptoms, seek medical care promptly.
How often should I retest?
If you're in a high-risk group, such as people on certain immune-suppressing therapies, periodic monitoring every few months may be recommended depending on your specific situation. If you've had a previous detectable result, more frequent retesting helps track whether the virus level is going up or down over time. Your trends dashboard makes it easy to see these changes at a glance.
What should I do if my results are abnormal?
If your JC virus DNA comes back detectable, especially at a high level, review the explanation in your report carefully and watch closely for any neurological symptoms like vision or coordination changes. Because PML can progress quickly in immunocompromised individuals, an abnormal result paired with symptoms warrants seeking medical care right away. Keeping up with your general immune health and any prescribed treatments also remains important.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
JC Polyoma Virus DNA (Urine) 1,250 IU/mL (3.10 Log IU/mL)
Demo results
Not Detected (<50 IU/mL) Detected (≥50 IU/mL)
1,250 IU/mL (3.10 Log IU/mL)

What this means

This result shows detectable JC virus DNA in the urine, meaning the virus is active rather than dormant. In people with healthy immune systems this is usually not a concern, but in immunocompromised individuals it warrants closer monitoring. The level can be tracked over time to see if it's rising or falling.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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JC Virus DNA Urine Test for Immunocompromised Monitoring

  • Detect active JC virus reactivation
  • Monitor brain infection risk levels
  • Track immune system virus activity
$1763
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.